Search for dissertations about: "IL6"

Showing result 1 - 5 of 42 swedish dissertations containing the word IL6.

  2. 1. Functional characterization of the liopsarcoma-associated fusion oncigene FUS-DDIT3

    Author : Melker Göransson; Göteborgs universitet; []
    Keywords : Myxoid round cell liposarcoma; fusion oncogenes; FUS; DDIT3; tumor development; cell cycle regulators; IL6; IL8; NFkappaB.;

    Abstract : Fusion genes represent a growing class of translocation-derived potent oncogenes that frequently show tumor type-specific expression. We have studied the myxoid/round cell liposarcoma (MLS/RCLS)-specific FUS-DDIT3 fusion, with the aim of functionally characterizing this fusion oncogene in sarcoma development. READ MORE

  4. 2. Inflammation and prostate carcinogenesis : influence of immune characteristics and early-adulthood exposure to inflammatory conditions on prostate cancer risk

    Author : Henrik Ugge; Katja Fall; Sabina Davidsson; Jessica Carlsson; Ove Andrén; Lars Henningsohn; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; inflammation; Cutibacterium acnes; acne; appendicitis; cytokines; circulating; inflammation marker; IL6; CXCL8;

    Abstract : Chronic inflammation has been implicated in the development of several types of cancer, and evidence from observational and animal studies suggests that it may play a role also in prostate carcinogenesis. Recent observations have brought Cutibacterium acnes (C. acnes) forward as a possible causative agent in pro-oncogenic prostatic inflammation. READ MORE

  5. 3. Interleukin 6 trans-signalling : cardiovascular risk marker or therapeutical target?

    Author : Louise Ziegler; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Interleukin (IL) 6 signals in two pathways. In classical signalling, essential in antimicrobial defence and tissue regeneration, IL6 binds the membrane- bound IL6 receptor (IL6R) which associates with the signal transducing receptor gp130. READ MORE

  6. 4. Cardiovascular effects of short-term exposure to air pollution : exploring potential pathways and susceptible subgroups

    Author : Petter Ljungman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cardiovascular disease is the most common cause of mortality globally, with a number of contributing risk factors. Ambient air pollution represents a universally present risk factor with a substantial preventive potential. READ MORE

  7. 5. Anastomotic leakage in colorectal surgery : early diagnosis and treatment with stent

    Author : Ioannis Oikonomakis; Kjell Jansson; Tal M. Hörer; Pär Myrelid; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; anastomotic leakage; colorectal cancer; intraperitoneal microdialysis; cytokines; mRNA analysis; stent;

    Abstract : Every year inn Sweden more than 6000 individuals are diagnosed with colorectal cancer and more than 5000 operations are performed. Anastomotic leakage (AL) is the most dreaded complication in colorectal surgery and has a great impact on postoperative morbidity and mortality. READ MORE