Search for dissertations about: "IL8"

Showing result 6 - 10 of 17 swedish dissertations containing the word IL8.

  2. 6. Liposarcomas - proliferation, senescence and the role of DDIT3

    Author : Christina Kåbjörn-Gustafsson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Liposarcoma; FUS-DDIT3; TP53; senescence;

    Abstract : Lipomatous tumors comprise benign and malignant forms called lipomas and liposarcomas. Myxoid/round cell liposarcoma (MLS/RCLS) is the second most common liposarcoma and is characterized by the fusion oncogenes FUS-DDIT3 or EWSR1-DDIT3. READ MORE

  4. 7. Co-stimulatory molecules : genes to protein in autoimmune and inflammatory disorders

    Author : Priya Sakthivel; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Co‐stimulatory molecules are antigen‐independent generators of secondary signals which aid in maintaining the homeostasis of the immune system. The most extensively studied co‐stimulatory pathway is CD28/CTLA‐4, expressed on the T cells, interacting with CD80/CD86, expressed on the antigen presenting cells (APC). READ MORE

  5. 8. Microbial and epigenetic factors in the pathogenesis of nasopharyngeal carcinoma

    Author : Xiaoying Zhou; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : While uncommon in most of the world, nasopharyngeal carcinoma (NPC) shows an unusual geographic and ethnic distribution, being highly prevalent in Southern China and Southeast Asia. Genetic susceptibility, Epstein-Barr virus (EBV) infection and additional environmental exposures are well established risk factors for NPC in endemic areas. READ MORE

  6. 9. Tumor microenvironment : the paradoxical action of fibroblasts

    Author : Twana Alkasalias; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The term tumor refers to an abnormal and pathological tissue characterized by a massive cell growth; it comprises various populations of transformed and malignant cells. These cells cross-communicate with each other and with different types of cells in the surrounding microenvironment. READ MORE

  7. 10. Novel signaling pathways : induced by bacterial toxins in eukaryotic cells

    Author : Camilla Oxhamre; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Inflammation is the process by which the host counteracts microbes that are constantly exposing the human body. These microbes rarely cause disease, due to the effective defense mechanisms of the host immune system. Although inflammation is essential for preventing infections, it can also damage the host. READ MORE