Search for dissertations about: "INNATE IMMUNITY TO VIRUS"

Showing result 1 - 5 of 66 swedish dissertations containing the words INNATE IMMUNITY TO VIRUS.

  2. 1. Mechanisms triggering the recruitment of mast cell progenitors to the lung and regulation of mast cell degranulation

    Author : Behdad Zarnegar; Jenny Hallgren; Madeleine Rådinger; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Mast cells; Mast cell progenitors; Recruitment; Lung; Virus; Influenza; Innate immunity; Poly I:C; IL-33; VAAT; SLC10A4; Degranulation;

    Abstract : Mast cells stem from the bone marrow and migrate via the blood as mast cell progenitors. Upon arrival in peripheral tissues, they develop into mast cells. These rare immune cells have numerous granules that contain large amounts of pro-inflammatory mediators. READ MORE

  4. 2. Harnessing the immunoregulatory capacity of single-stranded oligonucleotides to modulate innate immunity

    Author : Aleksandra Dondalska; Anna-Lena Spetz; Jenny Hallgren Martinsson; Stockholms universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; single-stranded oligonucleotides; Toll-like receptors; influenza; respiratory syncytial virus; dendritic cell; mast cell; virus infection; inflammation; itch; molekylär biovetenskap; Molecular Bioscience;

    Abstract : As the first line of defense, the innate immune system is exceptionally efficacious against invading pathogens but must be tightly regulated to avoid immune-related pathogenesis. Accordingly, the innate immune system recognizes highly conserved components associated with infections and damaged cells using a limited number of pattern-recognition receptors (PRRs), which are differentially expressed across cell types. READ MORE

  5. 3. Eco-immunological studies of innate immunity in Mallards (Anas platyrhynchos)

    Author : Anu S. Helin; Jonas Waldenström; Edwin Veldhuizen; Linnéuniversitetet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Avian β-defensins AvBDs ; Avian gene expression; Host-pathogen interactions; Innate immunity; Mallard Anas platyrhynchos ; Myxovirus resistance gene Mx ; Retinoic acid inducible gene 1 RIG-I ; Avian β-defensins AvBD ; Genuttryck; Gräsand Anas platyrhynchos ; Immunförsvar; Immungener; Myxovirus resistant gene Mx ; Patogen; Retinoic acid inducible gene 1 RIG-I ; Ecology; Ekologi;

    Abstract : This thesis comprises two sections, both of which explore eco-immunology of the innate immune system of mallards (Anas platyrhynchos). The innate immune system serves a pivotal role as the first line of defense against invading pathogens, and is comprised of physical and chemical barriers. READ MORE

  6. 4. Innate defense mechanisms of the nasal airway

    Author : Henrik Widegren; Lund näs- och halssjukdomar Öron-; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neutrophils; Leukotriene B4; CC10; TNF-alpha; innate immunity; allergic rhinitis; Airway inflammation;

    Abstract : Allergic and infectious rhinitis are prevalent conditions that besides a direct morbidity also causes exacerbations of asthma and chronic obstructive pulmonary disease. The immune mechanisms associated with various forms of rhinitis are not fully understood. READ MORE

  7. 5. Immunity to Rotavirus infection across ages

    Author : Konjit Getachew Muleta; Virusrekognition; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rotavirus; B cells; T cells; Dendritic cells; Mesenteric Lymph Node; CD8 T cells; Maternal protection; IgA; Neonates; Small Inestinal lamina propria; IFNAR signaling;

    Abstract : Rotavirus (RV) is a double-stranded RNA virus that mainly affects young children under the age of five years. It is one of the leading causes of dehydrating gastroenteritis. Every year, about 200,000 child deaths occur due to RVinfection. Vaccines exist and are in use worldwide. READ MORE