Search for dissertations about: "INTERFERONS"

Showing result 1 - 5 of 52 swedish dissertations containing the word INTERFERONS.

  2. 1. The Role of Maf Transcription Factors in Islet Inflammation and Βeta Cell Function

    Author : Tania Singh; Stamcellscentrum (SCC); []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Diabetes; T cells; pancreas; resident lymphocytes; autoimmunity; Insulin secretion; pancreas development; Type 1 and Type 2 diabetes; inflammation and leukocyte; Cytokines: immunology; Transcription Factor MAFs; Interferons;

    Abstract : Endocrine disorders that lead to a state of chronic high blood glucose levels are collectively referred to as diabetes. This metabolic disease is mainly categorized into type 1 (T1D) and type 2 diabetes (T2D). These diabetic forms originate from distinct triggering environmental, genetic, and altered mechanisms. READ MORE

  4. 2. Interferons in immunity to chlamydia pneumoniae

    Author : Antonio Carlos Gigliotti (Tony) Rothfuchs; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Chlamydia pneumoniae; TLR; IFN-alpha beta; IFN-gamma; macrophages; T cells;

    Abstract : The cytokine IFN-gamma is the architect behind an amazing immunological program of host resistance to intracellular bacterial and protozoan infections. IFN-gamma activates macrophages, making them into inhospitable habitats for parasites attempting to grow inside them. READ MORE

  5. 3. Induction of type I interferons and viral immunity

    Author : Åsa Hidmark; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Virus-induced type I interferons (IFNα/β) are key mediators of innate immunity and important modulators of adaptive immunity. Early recognition of virus and induction of IFNα/β are important for limiting the spread of the virus. READ MORE

  6. 4. Induction of type I interferons and viral immunity

    Author : Åsa Hidmark; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Virus-induced type I interferons (IFNα/β) are key mediators of innate immunity and important modulators of adaptive immunity. Early recognition of virus and induction of IFNα/β are important for limiting the spread of the virus. READ MORE

  7. 5. Mechanisms of type I interferons in autoimmunity and cancer

    Author : William A Nyberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Interferons (IFNs) were first described in the 1950’s and has since been characterized as potent inducers of pathogen defense mechanisms. Since then, researchers have uncovered a depth of mechanisms in the IFN system extending beyond immune modulation of pathogen defense. READ MORE