Search for dissertations about: "IONOTROPIC DRUGS"
Found 5 swedish dissertations containing the words IONOTROPIC DRUGS.
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1. Diffusion Controlled Drug Release from Slurry Formed, Porous, Organic and Clay-derived Pellets
Abstract : Coronary artery disease and chronic pain are serious health issues that cause severe discomfort and suffering in society today. Antithrombotic agents and highly potent analgesics play a critical role in improving the recovery process for patients being treated for these diseases. READ MORE
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2. Controlled release gel formulations and preclinical screening of drug candidates
Abstract : Simple gel formulations may be applied to enhance the systemic and local exposure of potential compounds. The aim of this thesis is the development and characterization of controlled release formulations based on thermo-reversible poloxamer gels, which are suitable for novel drug delivery applications. READ MORE
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3. Glutamate and GABA signalling components in the human brain and in immune cells
Abstract : Glutamate and γ-aminobutyric acid (GABA) are the principal excitatory and inhibitory neurotransmitters in the central nervous system (CNS). They both can activate their ionotropic and metabotropic receptors. READ MORE
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4. On neuroinflammation in psychotic disorders
Abstract : Neuroinflammation has been implicated in several psychiatric conditions. Based on experimental studies, the glia-derived tryptophan metabolite kynurenic acid (KYNA) may be especially relevant for positive psychotic symptoms and impaired executive functioning. READ MORE
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5. Mechanisms of Ischemic Brain Injury- studies in murine hippocampal slice cultures
Abstract : Cerebral ischemia is a major cause of mortality and morbidity in the western world. Even though much effort has been put into research and development of effective drugs against ischemic damage there is to date no effective pharmacological brain protective treatment. READ MORE