Search for dissertations about: "IPS-1"

Found 3 swedish dissertations containing the word IPS-1.

2. 1. Interplay between tick-borne encephalitis virus and the host innate immunity

   Author : Chaitanya Kurhade; Anna Överby Wernstedt; Nelson Gekara; Helen Lazear; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Virology; Flavivirus; IPS-1; Interferon; Viperin; mikrobiologi; Microbiology;

   Abstract : Flaviviruses are important emerging and re-emerging arthropod-borne pathogens that cause significant morbidity and mortality in humans. It consists of globally distributed human pathogens such as tick-borne encephalitis virus (TBEV), West Nile virus (WNV), Japanese encephalitis virus (JEV), yellow fever virus (YFV), dengue virus (DENV), and Zika virus (ZIKV). READ MORE

4. 2. Degradomics : a study of the cellular proteolytic landscape in enterovirus infections

   Author : Sebastian Kapell; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The common human pathogen, enteroviruses (EVs) are a genus of single stranded RNA viruses that include Coxsackie B virus (CVBs). The viral RNA encodes a polyprotein containing two viral proteases 2Apro and 3Cpro, that process the polyprotein into structural and non-structural proteins during virus replication. READ MORE

5. 3. Development of a therapeutic vaccine against the hepatitis C virus

   Author : Gustaf Ahlén; Karolinska Institutet; Karolinska Institutet; []
   Keywords : HCV; NS3; DNA vaccine; electroporation;

   Abstract : The hepatitis C virus (HCV) infection is a major cause of liver disease and it is estimated that 170 million people worldwide are chronically infected by HCV. There are no protective or curable vaccines available for HCV, however treatment consisting of interferon-α and ribavirin is curative in 45-75% of the chronic infected patients, depending on the viral genotype. READ MORE