Search for dissertations about: "IRDS"

Showing result 1 - 5 of 6 swedish dissertations containing the word IRDS.

  2. 1. Development and regulation of alveolar fluid clearance in the guinea pig

    Author : Andreas Norlin; Biologiska institutionen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; oxytocin-induced preterm labor; IRDS; fetal lung fluid; preterm lung development; amiloride-sensitive sodium channels; beta-adrenergic stimulation; alveolar epithelium; Animal physiology; Djurfysiologi;

    Abstract : Alveolar fluid clearance is driven by active absorption of Na+ across the alveolar epithelium. Development and hormonal regulation of alveolar fluid clearance over 1 hour was studied by instillation of a protein-containing, isosmolar fluid into lungs of fetal, newborn, and adult guinea pigs. READ MORE

  4. 2. Canine inherited retinal degenerations: a model for visual impairment in humans

    Author : Suvi Mäkeläinen; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Inherited retinal degenerations (IRDs) form a clinically and genetically heterogeneous group of diseases, leading to visual impairment or blindness in both humans and dogs. The prevalence of IRDs is estimated at 1 in 2,000 in humans. READ MORE

  5. 3. Mechanisms of multicellular drug resistance and novel approaches for targeted therapy in cancer

    Author : Elin Edsbäcker; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Dysregulated gene expression, due to genetic and epigenetic aberrations, as well as cancer cell-stroma interactions underlie both tumorigenesis and resistance to anti-cancer therapy. Although governed by common mechanisms, these features are unique to each individual tumor and therefore a personalized treatment regimen needs to be composed for each patient. READ MORE

  6. 4. Lung hyaluronan and lung water in the perinatal period

    Author : Hans Johnsson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrics and gynaecology; antenatal corticosteroids; antenatal terbutaline; hyaluronan; hyperoxia; lung water; perinatal period; Obstetrik och kvinnosjukdomar; Obstetrics and women s diseases; Obstetrik och kvinnosjukdomar; pediatrik; Pediatrics;

    Abstract : Hyaluronan is an important component of the lung extracellular matrix, with a high capacity for water immobilization, but information on perinatal changes in the lung hyaluronan concentration and their association with changes in the lung water content is limited. In this study, conducted both in rabbit pups and in human infants, we investigated changes in the hyaluronan concentration and distribution in the lung and in the lung water content after preterm or term birth, and changes produced by common antenatal and postnatal pathological conditions and treatments. READ MORE

  7. 5. Pneumococcal vaccination in inflammatory rheumatic disease. Antibody response and protection against infections

    Author : Johanna Nagel; Reumatologi och molekylär skelettbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vaccination; pneumococci; inflammatory rheumatic disease;

    Abstract : AbstractObjectives: Patients with inflammatory rheumatic diseases (IRDs) have higher risk of serious infections than healthy individuals due to their illness, comorbidities and treatments. Streptococcus pneumoniae is responsible for 30-50% of community aquired pneumonia in Europe. READ MORE