Search for dissertations about: "Idh1 mutation in glioma"

Found 2 swedish dissertations containing the words Idh1 mutation in glioma.

  1. 1. Profiling of microglia in inflammation, aging, and the tumor microenvironment

    Author : Lara Friess; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : In this thesis I aim to present our ongoing efforts to elucidate activation states and how these are regulated in microglia cells. An extensive body of work is dedicated to understanding how these resident immune cells can acquire certain activation states, as their roles are crucial for a great range of functions in the central nervous system – from homeostasis to pathological occurrences. READ MORE

  2. 2. Studies on the Roles of PDGFRA and EGFR in the Classification and Identification of Therapeutic Targets for Human Gliomas

    Author : Dongfeng Chen; Neurokirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gliomas; classification; EGFR; PDGFRA; FGF2; surface expression; cell proliferation;

    Abstract : Glioma is the most common type of primary tumor in the adult central nervous system (CNS). However, the current classification of gliomas is highly subjective and even inaccurate in some cases, which leads to clinical confusion and hinders the development of targeted therapies. READ MORE