Search for dissertations about: "Ig"

Showing result 21 - 25 of 163 swedish dissertations containing the word Ig.

  2. 21. Coping and emotional well-being in patients with chronic heart failure

    Author : Catarina Nahlen Bose; Fredrik Saboonchi; Gunilla Björling; Magnus L Elfström; Hans Persson; Jan Mårtensson; Karolinska Institutet Danderyd Hospital; Division of CardiovascularMedicine Dept of Clinical Sciences; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heart failure; Coping; Illness perception; Emotional well-being; Quality of life; Intervention; Randomized controlled trial; Heart failure;

    Abstract : Background: Chronic heart failure (CHF) is a serious illness, with a profound impact on the patient. Poor health-related quality of life (HRQoL) as well as anxiety and depression are prevalent in CHF and predict mortality and rehospitalization, yet, psychosocial factors are infrequently treated and cared for. READ MORE

  4. 22. Reconstitution of the B-cell repertoire following allogeneic bone marrow transplantation

    Author : Ingrid Näsman Björk; Karolinska Institutet; Karolinska Institutet; []
    Keywords : B cell repertoire allogeneic bone marrow transplantation immune reconstitution immunoglobulin genes serum immunoglobulin;

    Abstract : Allogeneic bone marrow transplantation (BMT) is an established therapy for patients with a variety of haematological malignancies. Patients undergoing BMT often suffer from severe infections that can be partly explained by humoral immune deficiency. READ MORE

  5. 23. Stereotyped B Cell Receptors in Chronic Lymphocytic Leukaemia : Implications for Antigen Selection in Leukemogenesis

    Author : Fiona Murray; Richard Rosenquist Brandell; Kostas Stamatopoulos; Gunilla Enblad; Gerard Tobin; Manlio Ferrarini; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chronic lymphocytic leukaemia; immunoglobulin genes; somatic hypermutation; stereotyped B cell receptors; antigen selection; Molecular biology; Molekylärbiologi;

    Abstract : Biased immunoglobulin heavy variable (IGHV) gene usage and distinctive B-cell receptor (BCR) features have been reported in chronic lymphocytic leukaemia (CLL), which may reflect clonal selection by antigens during disease development. Furthermore, the IGHV gene mutation status distinguishes two clinical entities of CLL, where patients with unmutated IGHV genes have an inferior prognosis compared to those with mutated IGHV genes. READ MORE

  6. 24. Contributions to certain problems in algebraic topology

    Author : Juan M. Alonso; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Algebraisk topologi;

    Abstract : We consider two problems. The first one is to determine when a fibration is also a (homotopy) cofibration. We use a classic result of T. Ganea to give a complete algebraic solution. READ MORE

  7. 25. Murine plasmacytomagenesis : an experimental model of B-cell neoplasia

    Author : Santiago C Silva; Karolinska Institutet; Karolinska Institutet; []
    Keywords : mouse plasmacytomas; chromosomal translocation; chimeric mice; MYC-transgenic mice; ;

    Abstract : A chromosomal translocation which results in the illegitimate activation of the c-myc proto-oncogene by one of the three immunoglobulin (Ig) loci is invariably associated with human Burkitt's Lymphoma (BL), mouse plasmacytoma (MPC) and rat immunocytomas (RIC). In the MPC system a genetic predisposition linked to the BALB/c strain has been suggested. READ MORE