Search for dissertations about: "IgE"

Showing result 21 - 25 of 243 swedish dissertations containing the word IgE.

  2. 21. Protein adducts in plasma as biomarkers of exposure to and risk of organic acid anhydrides

    Author : Seema Rosqvist; Neurokirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; GC-MS; IgG; IgE; exposure-response; serum albumin; biological monitoring; Hexahydrophthalic anhydride; methylhexahydrophthalic anhydride; OEL; Occupational health; industrial medicine; Yrkesmedicin; arbetsmiljömedicin;

    Abstract : Organic acid anhydrides (OAAs) are important industrial chemicals but also potent inducers of airways diseases. Many exposed workers develop specific IgE and IgG antibodies. Hexahydrophthalic anhydride (HHPA) and methylhexahydrophthalic anhydride (MHHPA) are two particularly sensitising OAAs. READ MORE

  4. 22. Anomalies in humoral immunity in the NOD mouse : contribution to the progression of type 1 diabetes

    Author : Radha Thyagarajan; Kristina Lejon; Per-Arne Oldenborg; Susanna Cardell; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 Diabetes; NOD mouse; B cells; IgE; TACI; BAFF; immunologi; Immunology;

    Abstract : The non-obese diabetic (NOD) mouse is widely used model Type 1 diabetes (T1D), a chronic inflammatory disease characterized by destruction of the insulin producing β cells in the islets of Langerhans by immune cells. The classical symptoms include increased glucose levels in urine and blood, frequent urination and enhanced thirst. READ MORE

  5. 23. Pathogenesis and Diagnosis of Food Hypersensitivity in Adults

    Author : Jenny Magnusson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Birch pollen allergy; DBPCFC; Diagnosis; Duodenal mucosa; Eosinophils; Faecal samples; Food induced gastrointestinal hypersensitivity; IgE; Neutrophil MPO; T lymphocytes;

    Abstract : Objective tools to diagnose local gastrointestinal (GI) inflammatory reactions in patients with food hypersensitivity are lacking. To fully appreciate the mechanisms mediating allergy-like reactions in the GI tract and for improvement of diagnostic techniques more knowledge is required. READ MORE

  6. 24. Generation and evolution of human antibody repertoires

    Author : Helena Persson; Institutionen för immunteknologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; specificity; Immunology; serology; transplantation; Immunologi; serologi; Biotechnology; Bioteknik; phage display; IgE; hapten; grass pollen allergen; diversity; antibody repertoire; antibody library; antibody evolution; affinity maturation; allergy;

    Abstract : This thesis, which is based on five original papers, covers different aspects of antibody specificity and diversity, with the overall goal to understand the makeup of antibody repertoires and their functionality as they occur in vivo or as they are developed in the laboratory. Besides their importance in the adaptive immune response, antibodies have emerged as an invaluable tool in applications ranging from basic research to disease diagnostics and therapy. READ MORE

  7. 25. Antibody repertoires : Exploration of their role in allergic disease and facilitation of reliable analyses thereof

    Author : Linnea Thörnqvist; Institutionen för immunteknologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; allergen; allergic disease; antibody bioinformatics; antibody repertoire; B cells; epitope; immunogloblulin; immunogloblulin germline gene; IgE; specific immunotherapy; stereotyped antibody;

    Abstract : Allergic disease affects millions of individuals worldwide and leads to both impaired life quality of the affected individuals and large economic costs for the society. Allergen-specific antibodies of IgE type act as one of the key players in the disease, by activating effector cells upon binding of its allergen. READ MORE