Search for dissertations about: "Immune-to-brain signaling"

Found 3 swedish dissertations containing the words Immune-to-brain signaling.

  2. 1. Immune-to-Brain Signaling in Fever : The Brain Endothelium as Interface

    Author : Elahe Mirrasekhian; David Engblom; Anders Blomqvist; Simin Mohseni; Tomas Deierborg; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Fever is a brain-regulated elevation of body temperature that occurs in response to infectious and non-infectious stimuli. During inflammatory episodes, circulating cytokines that are released by activated immune cells, trigger the induction of cyclooxygenase (COX)-2 in the ventromedial preoptic area of the hypothalamus (the thermoregulation center). READ MORE

  4. 2. Prostaglandin E2 in immune-to-brain signaling

    Author : David Engblom; Tamas Bartfai; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Upon immune-challenge, signaling from the immune system to the brain triggers an array of central nervous responses that include fever, anorexia, hyperalgesia and activation of the hypothalamus-pituitary adrenal axis. These symptoms are dependent on cytokines produced at the site of inflammation. READ MORE

  5. 3. Talking to the Brain at the Blood-Brain Barrier through Inflammation-Induced Prostaglandin E2

    Author : Ana Maria Vasilache; Camilla Nilsberth; Sivert Lindström; Fredrik Elinder; Ted Ebendal; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : The immune-to-brain signaling is a critical survival factor when the body is confronted by pathogens, and in particular by microorganisms. During infections, the ability of the immune system to engage the central nervous system (CNS) in the management of the inflammatory response is just as important as its ability to mount a specific immune response against the pathogen, since the CNS can provide a systemic negative feed-back to the immune activation by release of stress hormones and also can prioritize the usage of the energy resources by the vital organs. READ MORE