Search for dissertations about: "Immunization"

Showing result 16 - 20 of 246 swedish dissertations containing the word Immunization.

  1. 16. Development of a Passive Immunization Strategy Against Atherosclerosis

    University dissertation from Department of Clinical Sciences, Lund University

    Author : Alexandru Schiopu; Lund University.; Lunds universitet.; [2006]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; regression; plaque; peptide; oxidized LDL; immune system; carotid stenosis; cardiovascular diseases; apolipoprotein B-100; atherosclerosis; Kardiovaskulära systemet; Cardiovascular system; vascular injury; ultrasound; antibodies;

    Abstract : Atherosclerosis is a chronic inflammatory disease, characterized by the accumulation of lipids and fibrous tissue in the wall of medium and large-sized arteries. The characteristic culprit of the disease is the atheroma, or atherosclerotic plaque, a patchy thickening of the arterial wall which affects the lumen, inducing various degrees of stenosis. READ MORE

  2. 17. Tick-borne encephalitis : prognosis, immunization and virus strain characterization

    University dissertation from Stockholm : Karolinska Institutet, Department of Medicine at Huddinge University Hospital

    Author : Mats Haglund; Karolinska Institutet.; Karolinska Institutet.; [2000]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tick-borne encephalitis; tick-borne encephalitis virus; human; clinical picture; sequelae; virus characterization; phylogeny; vaccination; neutralization;

    Abstract : The aims were to investigate the morbidity associated with tick-borne encephalitis (TBE) both in the acute phase and at long-term follow-up, to develop a rapid neutralization test for confirmation of TBEV-specific antibody response and to study the serological response after TBE-vaccination and, finally, to characterize Swedish human TBEV isolates. The morbidity was studied in one retrospective follow-up study of consecutive TBE-patients, treated during a 10-year period (Paper 1) and in one prospective study of TBE-patients with aseptic meningoencephalitis of non- TBE etiology as a reference group (Paper II). READ MORE

  3. 18. Production and delivery of recombinant subunit vaccines

    University dissertation from Stockholm : Bioteknologi

    Author : Christin Andersson; KTH.; [2000]
    Keywords : Affibody; Affinity chromatography; Affinity purification; DNA immunization; Expression plasmid; Fusion protein; Hydrophobic tag; Iscoms; Lipid tagging; Malaria; Mammalian cell expression; Recombinant immunogen; Respiratory Syncytial Virus; Semliki Fo;

    Abstract : Recombinant strategies are today dominating in thedevelopment of modern subunit vaccines. This thesis describesstrategies for the production and recovery of protein subunitimmunogens, and how genetic design of the expression vectorscan be used to adapt the immunogens for incorporation intoadjuvant systems. READ MORE

  4. 19. Co-stimulation in gut mucosal immunity. Evidence of a differential regulationof local and systemic responses

    University dissertation from Göteborg

    Author : Eva Gärdby; Göteborgs universitet.; Gothenburg University.; [2000]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mucosal immunity; PP; cholera toxin; oral immunization; co-stimulation; Th1 Th2;

    Abstract : In recent years we have learned that co-stimulatory factors are required as second signals for optimal T cell stimulation. Most types of immune responses are, therefore, dependent on the co-stimulatory signals that are provided by infection or immunization. READ MORE

  5. 20. Induction of t-cell responses against PSA by plasmid DNA immunization

    University dissertation from Stockholm : Karolinska Institutet, Department of Oncology-Pathology

    Author : Maxim Pavlenko; Karolinska Institutet.; Karolinska Institutet.; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate-specific antigen; DNA vaccine; cytotoxic T lymphocytes;

    Abstract : This thesis is focused on using plasmid DNA encoding human prostate-specific antigen (PSA) for immunotherapy of prostate cancer. PSA is a secreted serine protease, which is produced almost exclusively by prostate epithelial cells. READ MORE