Search for dissertations about: "Immunization"

Showing result 26 - 30 of 266 swedish dissertations containing the word Immunization.

  2. 26. B cell fate following immunization : from memory B cells to plasma cells

    Author : Paola Martínez Murillo; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Most approved successful human vaccines induce neutralizing antibody titers maintained above a given threshold for long-term protection against potential pathogen exposure. The pathogens targeted by these vaccines are antigenically stable and the relevant epitopes are immunogenic. READ MORE

  4. 27. Immunization approaches and molecular signatures for mucosal immunity to primary and recurrent genital herpes

    Author : Josefine Persson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunologi;

    Abstract : Genital herpes is most commonly caused by herpes simplex virus type 2 (HSV-2), and is a prevalent sexually transmitted infection worldwide. Despite numerous efforts, there is currently no licensed vaccine against the disease. READ MORE

  5. 28. The development of a new combined adjuvant vector for mucosal immunization CTA1-DD/ISCOM

    Author : Anja Helgeby; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CTA1-DD; ISCOM; adjuvants; enzyme; vaccine; B cell; Dendritic cell; T cells;

    Abstract : The CTA1-DD/ISCOMs vector is a rationally designed mucosal adjuvant that was developed to host the distinctive properties of either adjuvant alone or in a combination that hosted additive enhancing effects on mucosal immune responses. Here I demonstrate that CTA1-DD can be incorporated into the ISCOM with greatly augmented immunogenicity of both incorporated and admixed antigen. READ MORE

  6. 29. Consumer reported digital immunization records : feasibility, applicability, and public health utility in the Canadian context

    Author : Katherine M Atkinson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Vaccination is one of the most effective public health interventions of all time. Public health programs collect data on Vaccination Coverage (VC) to determine levels of protection and guide resource allocation for further vaccination campaigns but VC data completeness and utility is a challenge in many settings. READ MORE

  7. 30. Helicobacter pylori infection and immunity. Protection after vaccination and regulation of inflammation in a mouse model

    Author : Sukanya Raghavan; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Helicobacter pylori; formalin-inactivated H. pylori; post-immunization gastritis; cholera toxin; CD4 CD25 regulatory T cells; CpG ODN;

    Abstract : Helicobacter pylori infection is an important cause of chronic active gastritis and peptic ulcer disease and a risk factor for the development of gastric cancer. An attractive strategy in the control of H. pylori infection is the development of a safe and effective therapeutic vaccine. Using a mouse model of H. READ MORE