Search for dissertations about: "Immunization"

Showing result 31 - 35 of 266 swedish dissertations containing the word Immunization.

  2. 31. Studies of T- and B-cells for the generation of human antigen specific antibodies

    Author : Eva Andersson; Institutionen för immunteknologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; germinal center; CD4 CD57 T cells; mucin 1; in vitro immunization; human class switched antibodies; Biotechnology; Bioteknik;

    Abstract : Human antibodies generated in vitro may be highly valuable for diagnostic and therapeutic purposes. For a long time most human antibodies produced in vitro have been of the IgM isotype with rather low affinities. In this thesis a method for production of IgG switched antigen-specific human antibodies is presented. READ MORE

  4. 32. PROTEIN VACCINE AGAINST NEONATAL GROUP B STREPTOCOCCAL INFECTION Immunization experiments in animals and a serological study in humans

    Author : Charlotte U Larsson; Avdelningen för medicinsk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bakteriologi; mycology; bacteriology; Microbiology; virologi; mykologi; neonatal infection; human antibody; intranasal; vaccine; cholera toxin B subunit; Rib; α; Group B streptococcus; surface protein; Mikrobiologi; virology;

    Abstract : Infection with group B streptococcus (GBS), an encapsulated bacterium, is an important cause of neonatal morbidity and mortality. Capsular polysaccharides and cell surface proteins of GBS are candidate antigens for development of a human GBS vaccine. Proteins have many advantages as vaccine antigens. READ MORE

  5. 33. Development of novel immunization approaches to generate immunity in the female genital tract with special reference to genital herpes

    Author : Sara Tengvall; Göteborgs universitet; []
    Keywords : female genital tract immunity; genital herpes; mucosal adjuvant; TLR; MyD88; CpG ODN;

    Abstract : Development of mucosal vaccines for inducing immunity in the female reproductive tract would have profound implications for the prevention of sexually transmitted diseases. Despite numerous efforts, no such vaccines are currently available for human use. READ MORE

  6. 34. HIV-1 patient assessment and treatment : from multitest to co-receptor (CCR5) gene polymorphism : from Rgp160 immunization to highly active antiretroviral treatment (HAART)

    Author : Göran Bratt; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : During the last 15 years, understanding of the pathogenesis of HIV- 1 infection and AIDS has developed rapidly. From a mysterious plague-like untreatable disease with unknown cause and transmission route to a well characterized, chronic, manageable, if yet not curable, retroviral infection. READ MORE

  7. 35. Immune responses induced by immunization with HIV-1 DNA followed by HIV-modified vaccinia virus Ankara with or without recombinant GP140 in healthy Tanzanian individuals

    Author : Agricola Joachim; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : A vaccine against HIV is widely considered the most effective and sustainable way of preventing new infections. We previously conducted a phase I/II clinical trial using multi-clade, multigene HIV-DNA priming and boosting with the recombinant modified vaccinia Ankara (HIV-MVA) virus among healthy Tanzanian volunteers (HIVIS03 trial). READ MORE