Search for dissertations about: "Immunoglobulin G: analysis"

Showing result 1 - 5 of 25 swedish dissertations containing the words Immunoglobulin G: analysis.

2. 1. Multivariate spectroscopic methods for the analysis of solutions

   Author : Kent Wiberg; Sven Jacobsson; Lars Nørgaard; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Chemometrics; UV-Vis spectroscopy; Multivariate calibration; Lidocaine; Identity; Content; PLS; SIMCA; Non-column; Diode array UV spectroscopy; DAD; Control sample; High Capacity Analysis HCA ; Fluorescence spectroscopy; Albumin; Immunoglobulin G; HPLC-DAD; Prilocaine; Peak purity determination; PCA; PARAFAC; Partial separation; Curve resolution; Analytical chemistry; Analytisk kemi;

   Abstract : In this thesis some multivariate spectroscopic methods for the analysis of solutions are proposed. Spectroscopy and multivariate data analysis form a powerful combination for obtaining both quantitative and qualitative information and it is shown how spectroscopic techniques in combination with chemometric data evaluation can be used to obtain rapid, simple and efficient analytical methods. READ MORE

4. 2. Contributions to 3D Image Analysis using Discrete Methods and Fuzzy Techniques : With Focus on Images from Cryo-Electron Tomography

   Author : Magnus Gedda; Ewert Bengtsson; Stina Svensson; Carolina Wählby; Punam Saha; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; digital image analysis; 3D; fuzzy; algorithms; grey-weighted distance; region growing; electron tomography; tracing; fluorescence microscopy; Datoriserad bildanalys; Computerized Image Analysis;

   Abstract : With the emergence of new imaging techniques, researchers are always eager to push the boundaries by examining objects either smaller or further away than what was previously possible. The development of image analysis techniques has greatly helped to introduce objectivity and coherence in measurements and decision making. READ MORE

5. 3. Immunoglobulin-binding bacterial surface proteins; biomedical tools and virulence factors

   Author : Britt-Marie Kihlberg; Infektionsmedicin; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Phagocytosis; M-like protein; M protein; Protein L; Protein G; Ig-binding; Streptococcus pyogenes; Fc Receptors; mykologi; virologi; bakteriologi; Mikrobiologi; mycology; virology; bacteriology; Microbiology; Cysteine proteinase; Streptolysin;

   Abstract : Many bacteria express immunoglobulin(Ig)-binding proteins that interact with Ig in a non-immune manner. Several of these Ig-binding bacterial proteins have been well characterized and are widely used as reagents for analysis and purification of Ig's. READ MORE

6. 4. Genetics of immunoglobulin a deficiency

   Author : Che Kang Lim; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Immunoglobulin A deficiency (IgAD) is the most common primary immunodeficiency in Caucasian populations. It is defined as a serum IgA level below 0.07 g/L with normal IgM and IgG levels in an individual older than four years of age. READ MORE

7. 5. Rational and Combinatorial Engineering of Affinity Proteins Towards Therapeutical Applications

   Author : Johan Seijsing; Torbjörn Gräslund; Uhlén Mathias; Inger Sandlie; KTH; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; neonatal Fc receptor; FcRn; affibody molecule; immunoglobulin G IgG ; serum albumin SA ; albumin binding domain ABD ; half-life extension; blocking; autoimmune disease; pH-dependence; GAD67; GAD-1; gene therapy; Parkinson’s disease; zinc finger based artificial transcription factor; Biotechnology; Bioteknologi;

   Abstract : Protein engineering has had an immense impact on the development of biological drugs, including replacement therapies with engineered versions of insulin or factor VIII to treat diabetes or bleeding disorders, and monoclonal antibodies to treat cancer and various other malignancies. Now, with the next generation of treatment modalities coming up, including monoclonal reagents based on alternative scaffolds, gene and cell therapies, the importance of protein engineering to tailor-make these treatments is likely to increase further. READ MORE