Search for dissertations about: "Immunohistochemistry"

Showing result 21 - 25 of 721 swedish dissertations containing the word Immunohistochemistry.

  2. 21. Chlamydia pneumoniae in Children - Epidemiology and Clinical Implications

    Author : Erik Normann; Björn Wettergren; Håkan Gnarpe; Claes Sundelin; Birger Trollfors; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pediatrics; allergy; asthma; children; Chlamydia pneumoniae; immunohistochemistry; microimmunofluorescence; polymerase chain reaction; respiratory tract infection; Pediatrik; Paediatric medicine; Pediatrisk medicin;

    Abstract : Chlamydia pneumoniae is a human respiratory tract pathogen. Seroepidemiological studies indicate that C. pneumoniae infection is most common in school-aged children and infrequently detected in younger children.The aims of this study were to further elucidate the prevalence of C. READ MORE

  4. 22. Aspects of Gene Expression Profiling in Disease and Health

    Author : Julia Bergman; Fredrik Pontén; Lars Akslen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; biomarkers; differential diagnostics; immunohistochemistry; transcriptomics; protein profiling; adrenal gland.; Pathology; Patologi;

    Abstract : The aim of this thesis is to in various ways explore protein expression in human normal tissue and in cancer and to apply that knowledge in biomarker discovery.In Paper I the prognostic significance of RNA-binding motif protein 3 (RBM3) is explored in malignant melanoma. READ MORE

  5. 23. Imaging of lipids and proteins in Alzheimer's disease using Time-of-Flight Secondary Ion Mass Spectrometry

    Author : Louise M Carlred; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; QCM-D; fluorescence microscopy; ToF-SIMS; Amyloid-β; immunohistochemistry; Sulfatides; antibodies; liposomes; Alzheimer’s disease; Cholesterol;

    Abstract : Alzheimer’s disease (AD) is a neurodegenerative disease characterized by the formation of senile plaques. These plaques, which consist of aggregations of a peptide called amyloid-β, are deposited in-between the nerve cells in the brain, where they disrupt the signaling processes. READ MORE

  6. 24. Novel Circulating and Tissue Biomarkers for Small Intestine Neuroendocrine Tumors and Lung Carcinoids

    Author : Tao Cui; Valeria Giandomenico; Kjell Öberg; Apostolos V. Tsolakis; Marco Volante; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; small intestine neuroendocrine tumors; lung carcinoids; Ma2 autoantibodies; immunohistochemistry; olfactory receptor 51E1; blood samples; antibody suspension bead array; 小肠神经内分泌肿瘤，肺类癌，Ma2自身抗体，免疫组化，嗅觉受体蛋白51E1， 血液样本，抗体悬浮磁珠阵列; Endokrinologi och Diabetologi; Endocrinology and Diabetology; Lung Medicine; Lungmedicin; Molecular Biology; Molekylärbiologi; Oncology; Onkologi;

    Abstract : Small intestine neuroendocrine tumors (SI-NETs) and lung carcinoids (LCs) are relatively indolent tumors, which originate from neuroendocrine (NE) cells of the diffuse NE system. Metastases can spread before diagnosis. Thus, potential cures become unavailable, which entitles new biomarker development. READ MORE

  7. 25. Studies on Tissue Factor with Focus on Cell Signaling and Cancer

    Author : Oskar Eriksson; Agneta Siegbahn; Lina Badimon; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Tissue Factor; blood coagulation; cell signaling; protease; mass spectrometry; immunohistochemistry; colorectal cancer; apoptosis; Eph receptor; Klinisk kemi; Clinical Chemistry; Molekylär cellbiologi; Molecular Cellbiology;

    Abstract : This thesis have explored the functions of the protein Tissue Factor (TF), which together with its ligand coagulation factor VII/VIIa (FVII/FVIIa) forms a proteolytic complex that functions in initiation of blood coagulation and activation of cell signaling.In paper I, the mechanisms behind the observation that TF/FVIIa signaling protects cells from apoptosis were further investigated. READ MORE