Search for dissertations about: "Immunologi serologi transplantation Immunology serology"

Showing result 16 - 20 of 126 swedish dissertations containing the words Immunologi serologi transplantation Immunology serology.

  1. 16. Reduced ROS production triggers arthritis / The role of T cells in arthritis pathogenesis

    Author : Jens Holmberg; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; Spleen and lymph nodes Inflammation Reactive oxygen species T cells MHC; serology; Immunology; Immunologi; serologi;

    Abstract : The aim of this thesis is to defend a novel mechanism that triggers arthritis susceptibility in both rats and mice through reduced production of reactive oxygen species (ROS), but also to introduce a novel model for chronic relapsing arthritis. Five papers are included, all of which employ animal models for rheumatoid arthritis and one that also uses animal models for multiple sclerosis. READ MORE

  2. 17. Novel strategies to explore The complex genetics of autoimmune diseases

    Author : Martina Johannesson; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; Immunology; serology; Immunologi; serologi; cytogenetik; Genetik; cytogenetics; Genetics; collagen induced arthritis; QTL mapping; complex traits; autoimmunity; genetics;

    Abstract : Autoimmune diseases are dependent on both genetic and environmental factors in complex interplay. They arise from a faulty immune response against self-antigens, and causes great suffering in affected individuals. Despite large efforts and hundreds of thousands of research articles published, the disease etiologies remain largely unknown. READ MORE

  3. 18. Immunity to Salmonella infection

    Author : Cecilia Johansson; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; serology; transplantation; Immunologi; serologi; cytokines; antigen presentation; liver; dendritic cells; Salmonella; gram negative bacteria;

    Abstract : The immune system has several strategies to combat infections. The present study investigates various aspects of the interaction between Gram negative bacteria, particularly Salmonella, and antigen presenting cells (APC). Salmonella is an intracellular bacterium infecting mice and man. READ MORE

  4. 19. Regulation of immunoglobulin transcription

    Author : David Liberg; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; N-substituted benzamides; NFkB; transcription; B cells; immunoglobulin; Immunology; serology; transplantation; Immunologi; serologi;

    Abstract : Each Ig V-region has its own upstream promoter and the promoter of a mature Ig gene is thereby selected during the V(D)J recombination process. Upon comparison, it is evident that only one transcription factor binding site, the octamer, is preserved within all promoters. READ MORE

  5. 20. Regulation of lymphocyte activation and death

    Author : Hanna Lindgren; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; N-substituted benzamides; apoptosis; NF-kB; NFAT; T cells; CD40L; serology; transplantation; Immunologi; serologi;

    Abstract : T lymohocytes (T cells) and B lymphocytes (B cells) are important effector cells of the adaptive immune system. In response to infections, B cells are activated and produce antibodies against specific antigens. READ MORE