Search for dissertations about: "Immunoprecipitation"

Showing result 1 - 5 of 138 swedish dissertations containing the word Immunoprecipitation.

  2. 1. Targeted Abeta proteomics - A tool to study the pathogenesis of Alzheimer’s disease

    Author : Erik Portelius; Göteborgs universitet; []
    Keywords : Alzheimer’s disease; Cerebrospinal fluid; Immunoprecipitation; Mass spectrometry; beta-amyloid;

    Abstract : Alzheimer’s disease (AD) is an age-related progressive neurodegenerative disorder of the central nervous system. Diagnosis and monitoring of sporadic AD has long depended on clinical examination of individuals with end-stage disease. READ MORE

  4. 2. High-throughput protein analysis using mass spectrometry-based methods

    Author : Tove Boström; Sophia Hober; Thomas Laurell; Ole N. Jensen; KTH; []
    Keywords : Proteomics; mass spectrometry; affinity proteomics; immunoenrichment; immunoprecipitation; IMAC; screening; protein production; protein purification; ISET; quantification; SILAC; stable isotope standard; antibody validation; Bioteknologi; Biotechnology;

    Abstract : In the field of proteomics, proteins are analyzed and quantified in high numbers. Protein analysis is of great importance and can for example generate information regarding protein function and involvement in disease. Different strategies for protein analysis and quan- tification have emerged, suitable for different applications. READ MORE

  5. 3. Analytical Approaches to Neurodegenerative Disease Protein Aggregation

    Author : Henning Wiberg; Åsa Emmer; Torbjörn Gräslund; Leopold Ilag; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; neurodegenerative diseases; protein misfolding; protein aggregation; gel electrophoresis; isoelectric focusing; immunodetection; ELISA; immunoprecipitation; mass spectrometry; nanoelectrospray; liquid chromatography; neurodegenerativa sjukdomar; felveckade proteiner; proteinaggregering; geleektrofores; isoelektrisk fokusering; immundetektion; ELISA; immunoprecipitering; masspektrometri; nanoelektrospray; vätskekromatografi; Analytical chemistry; Analytisk kemi;

    Abstract : .... READ MORE

  6. 4. Topology and membrane rearrangements of the hepatitis C virus protein NS4B

    Author : Marika Lundin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Hepatitis C virus; NS4B; NS5A; topology; posttranslational translocation membrane rearrangements; endoplasmic reticulum; polyprotein; membrane protein; membrane associated foci; oligomerization; viral replication; replicon; replication complex; mutations; immunoprecipitation;

    Abstract : Hepatitis C virus (HCV) is a major cause of chronic liver disease and viral hepatitis around the world. Approximately 180 million people or 3% of the world's population are infected with the virus. READ MORE

  7. 5. Functional interaction studies of different transmembrane proteins, activities occurring in the pore membrane and in the inner nuclear membrane

    Author : Ellinor Crafoord; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Aim: The overall aim of my research has been to investigate protein‐protein interactions of nuclear envelope proteins. One specific aim has been to study the effect of mitotic phosphorylation on binding of the pore membrane protein gp210 to the nuclear pore complex. READ MORE