Search for dissertations about: "Immunosurveillance"

Showing result 1 - 5 of 12 swedish dissertations containing the word Immunosurveillance.

  1. 1. Potentially Malignant Disorders and Oral cancer -A study on Immunosurveillance

    Author : Jenny Öhman; Göteborgs universitet.; Gothenburg University.; [2015]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oral lichen planus; Leukoplakia; Oral cancer; Immunosurveillance; Solid organ transplantation; T cells; Langerhans cells;

    Abstract : ABSTRACT The cancer immunosurveillance hypothesis postulates that the immune system can recognize cancer cell precursors and destroy those cells before a clinical manifestation occurs. During the last decades several groups have presented evidence of the influence and role of immune activation in oral squamous cell carcinoma (OSCC) patients; however, much less is known about the role of immune activation in potentially malignant oral disorders (PMOD). READ MORE

  2. 2. Exploring the role of mesenchymal stromal cells in endometriosis

    University dissertation from Stockholm : Karolinska Institutet, Dept of Clinical Science, Intervention and Technology

    Author : Fawaz Abomaray; Karolinska Institutet.; Karolinska Institutet.; [2018]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Endometriosis is a chronic inflammatory disease where there is growth of endometrial tissue in ectopic sites, most commonly within the pelvic cavity. The major symptoms of this disease are chronic pelvic pain and infertility. READ MORE

  3. 3. T-cell mediated control of Epstein-Barr virus infection : viral mechanisms of immune escape

    University dissertation from Stockholm : Karolinska Institutet, Microbiology and Tumor Biology Center (MTC)

    Author : Jelena Vladmirovna Levitskaya; Karolinska Institutet.; Karolinska Institutet.; [1999]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epstein-Barr virus; Cytotoxic T lymphocyte; CTL epitope; viral immunescape;

    Abstract : Mechanisms regulating the immunogenicity of Epstein-Barr Virus (EBV)-encoded CTL peptide epitopes and their contribution to the escape of virus infected cells from CTL-mediated immunosurveillance were the subject of these studies. It was demonstrated that two HLA A11-restricted CTL epitopes of EBV nuclear antigen (EBNA)-4 (designated IVT and AVF) possessed different immunogenicity that appeared to be due to a rapid surface turnover of All molecules containing the AVF peptide. READ MORE

  4. 4. Fatal attraction : NK cell migration toward and activity in solid tumors

    University dissertation from Stockholm : Karolinska Institutet, Dept of Oncology-Pathology

    Author : Veronika Kremer; Karolinska Institutet.; Karolinska Institutet.; [2018]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Natural killer (NK) cells play a key role in tumor immunosurveillance due to their ability to induce apoptosis of tumor cells and produce pro-inflammatory cytokines, without prior immune sensitization. In particular, NK cells demonstrate potent anti-tumor immune responses against metastases and hematological malignancies. READ MORE

  5. 5. T cells in solid tumors : investigating the immunomodulation in the tumor microenvironment

    University dissertation from Stockholm : Karolinska Institutet, Dept of Medicine, Solna

    Author : Ciputra Adijaya Hartana; Karolinska Institutet.; Karolinska Institutet.; [2018]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The immune system protects human from cancer through an immunosurveillance mechanism. However, the progressive nature of tumor cells to differentiate and the complexity of the tumor microenvironment may result in the immunomodulation of immune cells. READ MORE