Search for dissertations about: "In Vivo Induced Antigen Technology"

Found 5 swedish dissertations containing the words In Vivo Induced Antigen Technology.

  1. 1. Function and Regulation of B-cell Subsets in Experimental Autoimmune Arthritis

    Author : Anna-Karin E. Palm; Sandra Kleinau; Susanna Cardell; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; B cells; marginal zone; autoimmune arthritis; spleen; lymph node; antigen presentation; Fc gamma receptor IIb; complement receptors 1 and 2; mast cells; Biologi med inriktning mot molekylär immunologi; Biology with specialization in Molecular Immunology;

    Abstract : B lymphocytes play a significant role in autoimmune arthritis, with their function stretching beyond autoantibody production to cytokine secretion and presentation of autoantigen. However, the involvement and activation of different B-cell subset in the autoimmune response is not fully clear. READ MORE

  2. 2. Functionally-associated target antigens in cancer. Defined by human antibodies and small interfering RNAs

    Author : Johan Fransson; Institutionen för immunteknologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; phage display; Antibody; cancer; transplantation; Immunologi; serologi; serology; Immunology; onkologi; Cytologi; cancerology; oncology; Biochemistry; Metabolism; Biokemi; metabolism; Biotechnology; Bioteknik; Cytology;

    Abstract : Cancer is the collective name for diseases that have one thing in common ? uncontrolled cell growth. The increase in cancer cell proliferation eventually results in tumor formation and, in the worst case, metastatic spread to other organs. Common treatment modalities of cancer include chemotherapy and radiation therapy. READ MORE

  3. 3. Enhancing T cell mediated immunity in DNA vaccination

    Author : Jan Alvar Lindencrona; Karolinska Institutet; Karolinska Institutet; []
    Keywords : DNA vaccination; CTL; T cell; IFN-gamma; anti-tumor immunity; HER-2 neu; Influenza; LCMV; Virus-Like Particles; murine models; adjuvants; immunotherapy;

    Abstract : For centuries infectious diseases have been one of the main causes of death in the world. With the invention of vaccine technology 200 years ago, we have been able to impede and even eradicate several dangerous pathogens. READ MORE

  4. 4. Toxicity of smokeless tobacco in human oral epithelium with emphasis on carcinogen metabolism and regulation of programmed cell death

    Author : Martin Vondracek; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The oral mucosa is globally a common site for cancer development. Primary risk factors include tobacco smoking and alcohol consumption whereas the contribution from usage of smokeless tobacco remains debated. READ MORE

  5. 5. Characterization and targeting of leukemia propagating cells

    Author : Stina Virding Culleton; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Patients with hematopoietic malignancies have a large, unmet medical need. Allogeneic hematopoietic stem cell transplantation remains the only curative option, but many patients are not eligible for such treatment. READ MORE