Search for dissertations about: "In silico"
Showing result 11 - 15 of 198 swedish dissertations containing the words In silico.
-
11. Abdominal Aortic Wall Mechanics - Stress, Strain and Stiffness in A Medical Perspective : An Experimental Study in Man
Abstract : Background: The stiffness of the abdominal aorta is considered a significant factor affecting the morbidity and mortality of cardiovascular disease. Estimating vascular stiffness is an integral part in cardiovascular risk assessment. READ MORE
-
12. In silico Studies of Early Eukaryotic Evolution
Abstract : A question of great interest in evolutionary biology is how and why the eukaryotic cell evolved. Several hypotheses have been proposed, ranging from an early emergence of a primitive eukaryotic cell, to various fusion models like the hydrogen hypothesis. Within this context, relevant bacterial gene families and genomes are examined in this thesis. READ MORE
-
13. A step forward in using QSARs for regulatory hazard and exposure assessment of chemicals
Abstract : According to the REACH regulation chemicals produced or imported to the European Union need to be assessed to manage the risk of potential hazard to human health and the environment. An increasing number of chemicals in commerce prompts the need for utilizing faster and cheaper alternative methods for this assessment, such as quantitative structure-activity or property relationships (QSARs or QSPRs). READ MORE
-
14. Biopharmaceutical investigations of doxorubicin formulations used in liver cancer treatment : Studies in healthy pigs and liver cancer patients, combined with pharmacokinetic and biopharmaceutical modelling
Abstract : There are currently two types of drug formulation in clinical use in the locoregional treatment of intermediate hepatocellular carcinoma (HCC). In the emulsion LIPDOX, the cytostatic agent doxorubicin (DOX) is dissolved in the aqueous phase, which is emulsified with the oily contrast agent Lipiodol® (LIP). READ MORE
-
15. Biobased Adipic Acid - Challenges in Establishing a Cell Factory
Abstract : Growing concern regarding climate change calls for sustainable solutions to significantly reduce our dependency on non-renewable fossil-based raw materials. One potential solution is the development of biorefineries where biobased, renewable raw materials are converted into valuable products via enzymatic, chemical or microbial conversion. READ MORE