Search for dissertations about: "In vitro intestinal lipolysis"

Found 4 swedish dissertations containing the words In vitro intestinal lipolysis.

  2. 1. Predicting oral performance of lipid-based formulations using in vitro methods

    Author : Oliver Hedge; Christel Bergström; Frédéric Carriere; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; lipid-based formulation s ; SEDDS; artificial membrane s ; cell monolayer s ; oral drug delivery; lipolysis; permeation; Farmaceutisk vetenskap; Pharmaceutical Science;

    Abstract : Oral administration of drugs is widely considered preferable to other methods by end-users and healthcare providers alike; however, not all drug compounds are inherently suited for it because some molecules are not well-absorbed by the intestine. Good absorption requires both dissolution and permeation. READ MORE

  4. 2. Oxidation of marine oils during in vitro gastrointestinal digestion and its effects on stress in human intestinal Caco-2 cells

    Author : Cecilia Tullberg; Chalmers tekniska högskola; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; lipid oxidation; human digestive fluids; LC n-3 PUFAs; Caco-2 cells; marine oils; HNE; MDA; in vitro digestion; HHE; gastrointestinal; aldehydes;

    Abstract : Marine oils are attracting public interest due to the preventive effects, e.g., on inflammation, which are linked to the long-chain n-3 polyunsaturated fatty acids (LC n-3 PUFAs). However, LC n-3 PUFAs are highly susceptible to oxidation, which could interfere with their positive effects. READ MORE

  5. 3. Starch Pickering Emulsions : Process and Encapsulation Stability

    Author : Ali Marefati; Avdelningen för livsmedel och läkemedel; []
    Keywords : Starch granules; Pickering emulsions; Encapsulation; Freeze-thaw stability; Freeze-drying; In vitro digestion; In vitro intestinal lipolysis;

    Abstract : The emulsion stabilization functionality of surfactants and biopolymers can be replaced by solid particles adsorbed at the interface, where they create a category of emulsions known as Pickering emulsions. Recently, health and environmental concerns have led to new market demand for natural, biodegradable and renewable sources of ingredients. READ MORE

  6. 4. Advanced Methods for Evaluation of the Performance of Complex Drug Delivery System

    Author : Caroline Alvebratt; Christel Anna Sofia Bergström; Maria Strömme; Caitriona O'Driscoll; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; amorphous solid dispersion; coadministration; digestion; dissolution; drug absorption; enabling formulation; in vitro assay; lipid-based formulation; mesoporous carrier; supersaturation; Farmaceutisk vetenskap; Pharmaceutical Science;

    Abstract : Low oral bioavailability of drugs originating from poor aqueous solubility is a common issue in drug development. Various enabling formulations have been presented to circumvent this limitation, many making use of supersaturation. In these, the drug is delivered to the gastro-intestinal lumen in a high energy state e.g. READ MORE