Search for dissertations about: "Inactivated"

Showing result 1 - 5 of 159 swedish dissertations containing the word Inactivated.

  2. 1. The Role of Innate Immunity in Islet Transplantation : Clinical and Experimental Studies

    Author : Lisa Moberg; Bo Nilsson; Olle Korsgren; Kristina Nilsson Ekdahl; Rolf Larsson; David Harlan; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; diabetes; islet transplantation; islet of Langerhans; coagulation activation; IBMIR; tissue factor; thrombin; inactivated FVIIa; melagatran; neutrophilic granulocyte; Immunologi; Immunology; Immunologi;

    Abstract : Clinical islet transplantation is an emerging procedure to cure type 1 diabetes. The graft is implanted by infusion into the liver through the portal vein. A major obstacle that still needs to be overcome is the requirement for islets from multiple donors to achieve insulin independence. READ MORE

  4. 2. Processing of live and heat inactivated Sendai virus for presentation on MHC class I molecules

    Author : Tianmin Liu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : antigen presentation; antigen processing; APC; CTL; MHC class1; peptides; Sendai virus; TAP;

    Abstract : The present thesis deals with processing of antigens from live and heat inactivated Sendai virus and their loading on MHC class I molecules for presentation to CTL. In paper I it was observed surprisingly that T2 cells (T2 cells transfected with H-2Kb), being defective in the expression of TAP peptide transporters, still presented Sendai virus antigen on MHC class I molecules to CTL. READ MORE

  5. 3. Helicobacter pylori infection and immunity. Protection after vaccination and regulation of inflammation in a mouse model

    Author : Sukanya Raghavan; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Helicobacter pylori; formalin-inactivated H. pylori; post-immunization gastritis; cholera toxin; CD4 CD25 regulatory T cells; CpG ODN;

    Abstract : Helicobacter pylori infection is an important cause of chronic active gastritis and peptic ulcer disease and a risk factor for the development of gastric cancer. An attractive strategy in the control of H. pylori infection is the development of a safe and effective therapeutic vaccine. Using a mouse model of H. READ MORE

  6. 4. Crosstalk between Inflammation and Coagulation in Acute Pancreatitis - Experimental and Clinical Studies

    Author : Ellen Andersson; Lund Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; inflammation; acute pancreatitis; active site inactivated factor VII; bleeding; coagulation; factor VII; FVIIai; hemorrhagic complications; hemorrhage; interleukin-6; MIP-2; nuclear factor kappa B; tissue factor;

    Abstract : In various inflammatory conditions a close interplay between inflammation and coagulation is known to exist, where coagulation factor VII (FVII) and tissue factor (TF) are considered to be pivotal players. In this thesis the crosstalk between inflammation and coagulation in acute pancreatitis (AP) has been investigated. READ MORE

  7. 5. Effects of feeding yeasts on blood physiology and gut microbiota of rainbow trout

    Author : David Huyben; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Abstract : Yeast represents a sustainable protein alternative to fishmeal in diets for farmed fish, although more than 40% replacement has been shown to reduce fish growth and welfare. This thesis investigated the effects of feeding high inclusions of inactivated and live yeasts to fish in order to replace fishmeal without negative health consequences. READ MORE