Search for dissertations about: "Infections in haematological malignancies"

Showing result 1 - 5 of 9 swedish dissertations containing the words Infections in haematological malignancies.

2. 1. Infections in patients with haematological malignancies

   Author : Honar Cherif; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Haematological malignancies; febrile neutropenia; bacteraemia; Candida; oral antibiotic; risk stratification; FUO; cefepime; splenectomy; pneumococcal vaccine;

   Abstract : Infectious complications are an important cause of morbidity and mortality in patients with hematological diseases, especially during chemotherapy induced neutropenia. This study was undertaken with the ultimate goal to improve the clinical management of infections in patients with hematological diseases. READ MORE

4. 2. Aetiology and infection susceptibility in neutropaenic patients

   Author : Michelle Wong; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Increasingly intensive antineoplastic regimes have been effective in the treatment for haematological malignancies, but as effective as it is in limiting neoplasm of the malignant cells, bystander damage occurs equally to cells of the immune system and epithelial cells of the mucosa. Infectious complications following chemotherapy reflect this situation. READ MORE

5. 3. Translational studies on antimetabolic therapies in paediatric oncology

   Author : Nikolaos Tsesmetzis; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Cure rates for paediatric and adult cancer patients have improved within the last decades. This can partly be explained by implementation of new technologies and methodologies such as the identification of new mutations after sequencing that can be directly targeted for treatment or the introduction of immunotherapy. READ MORE

6. 4. Anti-tumour effect in solid tumours, tolerance and immune reconstition after allogeneic haematopoietic stem cell transplantation

   Author : Patrik Hentschke; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Both in haematological malignancies and in disseminated solid tumours, re-occurrence of the underlying disease is the main complication. Allogeneic haematopoietic stem cell transplantation (HSCT) increases the chance of cure compared to only chemotherapy in haematological malignancies, but adds the risk of immunological complications such as graft-versus-host disease (GVHD) and severe infections. READ MORE

7. 5. Natural killer cell development and function in the context of allogenic stem cell transplantation and cell therapy

   Author : Alvaro Haroun-Izquierdo; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Natural killer (NK) cells play a crucial role in the control of viral infections and transformed, cancerous cells. These innate cells have high cytotoxic capacities and use a multitude of receptors to interact with neighbouring cells. READ MORE