Search for dissertations about: "Infektionsmedicin"

Showing result 21 - 25 of 277 swedish dissertations containing the word Infektionsmedicin.

  2. 21. Unraveling the immune response in sepsis and meningitis. Diagnostic and therapeutic approaches

    Author : Jane Fisher; Infektionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; meningtis; sepsis; neutrophil extracellular traps NETs ; glymphatic system; DNase; pneumococci;

    Abstract : Severe infections continue to constitute a large burden, with high mortality and risk of sequelae. Sepsis is a dysregulated host response to an infection that causes life threatening organ damage. Meningitis is a severe infection of the brain that often leads to sepsis and death or lasting neurological damage. READ MORE

  4. 22. On norovirus outbreaks and transmission in hospitals

    Author : Carl-Johan Fraenkel; Infektionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; norovirus; outbreaks; transmission; surveillance; prevention;

    Abstract : Abstract Noroviruses are now the leading cause of gastroenteritis worldwide. Noroviruses are effectively transmitted due to a low infectious dose, viral shedding in high concentrations, environmental stability, and they induce only a limited immunity after infection. Especially, the norovirus variants of genotype II.4 (GII. READ MORE

  5. 23. Evolutionary and functional studies of protein H: a surface molecule of Streptococcus pyogenes

    Author : Inga-Maria Frick; Infektionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; intracellular transportation; adhesion; aggregation; FNIII domain; albumin-binding; M-like protein; convergent evolution; protein G; Streptococcus pyogenes; IgG-binding; Microbiology; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Abstract : Several bacterial species express surface proteins with affinity for the Fc part of human IgG. This thesis describes evolutionary and functional studies of protein H, an IgGFc-binding surface protein of the human pathogen Streptococcus pyogenes. READ MORE

  6. 24. Molecular targets for glucocorticoids in macrophages: cytosolic phospholipase A2 and cytokine formation

    Author : Karin Gewert; Infektionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacognosy; Pharmacological sciences; signal transduction; dexamethasone; cytosolic phospholipase A2; glucocorticoids; macrophages; protein kinase C; mitogen-activated protein kinases; TNF-alpha; IL-1beta; protein phosphatases; okadaic acid; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

    Abstract : The aim of this investigation has been to study mechanisms by which glucocorticoids inhibit inflammatory processes in vitro. Type IV cytosolic 85 kDa phospholipase A2 (cPLA2) is an important modulator of inflammatory responses that is present in macrophages as well as in other cell types. READ MORE

  7. 25. Alpha-1-microglobulin: Innate defence against pathological oxidation

    Author : Magnus Gram; Infektionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; alpha-1-microglobulin; pathological oxidation; hemoglobin; heme; radiation; oxidation; ROS; hemoglobin and heme antagonist; radical scavenger;

    Abstract : Oxidative stress has been implicated as an important factor in the progression of many diseases. An imbalance in the redox-system may cause oxidation of cells and molecules, which might subsequently lead to tissue damage. READ MORE