Search for dissertations about: "Inference"

Showing result 21 - 25 of 547 swedish dissertations containing the word Inference.

  2. 21. Bayesian inference for detection problems in biology

    Author : Ronny Hedell; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; PCR; Bayesian inference; Forensic DNA analysis; Syndromic surveillance; Bacillus anthracis; Markov chain Monte Carlo; Allele dropout; Bacillus anthracis;

    Abstract : This thesis is about different kinds of detection problems in biology: detection of DNA sequences in crime scene samples, detection of harmful bacteria in feed and food stuff and detection of epidemical diseases in animal populations. In each case, biological data is produced or collected in order to determine which DNA sequences, bacteria types or diseases are present, if any. READ MORE

  4. 22. Two Optimization Problems in Genetics : Multi-dimensional QTL Analysis and Haplotype Inference

    Author : Carl Nettelblad; Sverker Holmgren; José M. Álvarez-Castro; Jukka Corander; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; quantitative trait loci; genome-wide association studies; hidden Markov models; numerical optimization; linkage analysis; haplotype inference; genotype imputation; high performance computing;

    Abstract : The existence of new technologies, implemented in efficient platforms and workflows has made massive genotyping available to all fields of biology and medicine. Genetic analyses are no longer dominated by experimental work in laboratories, but rather the interpretation of the resulting data. READ MORE

  5. 23. Exploring the Boundaries of Gene Regulatory Network Inference

    Author : Andreas Tjärnberg; Erik Sonnhammer; Richard Bonneau; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; GRN; gene regulatory network; network inference; signal to noise ratio; model selection; variable selection; data properties; reverse engineering; ordinary differential equations; gene networks; linear regression; lasso; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

    Abstract : To understand how the components of a complex system like the biological cell interact and regulate each other, we need to collect data for how the components respond to system perturbations. Such data can then be used to solve the inverse problem of inferring a network that describes how the pieces influence each other. READ MORE

  6. 24. Sensitivity Analysis of Untestable Assumptions in Causal Inference

    Author : Mathias Lundin; Xavier de Luna; Maria Karlsson; Sune Karlsson; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Observational studies; semiparametric regression; unconfoundedness; Causal inference; Statistics; Statistik; Statistics; statistik;

    Abstract : This thesis contributes to the research field of causal inference, where the effect of a treatment on an outcome is of interest is concerned. Many such effects cannot be estimated through randomised experiments. For example, the effect of higher education on future income needs to be estimated using observational data. READ MORE

  7. 25. Inference of functional association networks and gene orthology

    Author : Thomas Schmitt; Erik L. L. Sonnhammer; Søren Brunak; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; orthology; InParanoid; FunCoup; systems biology; biological networks; network inference; functional coupling; functional association; biokemi; inriktning teoretisk kemi; Biochemistry with Emphasis on Theoretical Chemistry;

    Abstract : Most proteomics and genomics experiments are performed on a small set of well-studied model organisms and their results are generalized to other species. This is possible because all species are evolutionarily related. When transferring information across species, orthologs are the most likely candidates for functional equivalence. READ MORE