Search for dissertations about: "Inflammatory biomarkers"

Showing result 21 - 25 of 247 swedish dissertations containing the words Inflammatory biomarkers.

2. 21. Evaluation of biomarkers in chronic inflammatory diseases

   Author : Zahra Golabkesh; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The overall aim of this thesis was to assess the role of biomarkers in chronic inflammatory disease. The goal of the first study was to investigate the association of sIL-6R and sgp130 levels and risk of first myocardial infarction (MI), and to explore the potential interaction between these two biomarkers in association with risk of MI. READ MORE

4. 22. The effect of common and rare variants on inflammatory traits and diseases

   Author : Julia Höglund; Åsa Johansson; Matthew Robinson; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; GWAS; inflammation; biomarkers; WES; WGS; NSPHS; UK Biobank; association study;

   Abstract : Genome wide association studies (GWAS) have identified thousands of loci associated to an immense number of traits and diseases. Most associations have been to common variants, but rare variant associations are progressively being reported. READ MORE

5. 23. Biomarkers in mid-trimester amniotic fluid in relation to gestational duration and spontaneous preterm delivery

   Author : Maria Hallingström; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; amniotic fluid; biomarkers; cytokine; damage-associated molecular pattern; gestation; gestational duration; inflammation; labor; mid-trimester; multiplex; pregnancy clock; proteins; spontaneous preterm delivery; term delivery;

   Abstract : Background: The biological mechanisms and physiological pathways of pregnancy maintenance and timing of delivery are complex and multifactorial. Pregnancy clocks, partly controlled by timing mechanisms linked to fetal development, which regulate the onset of labor has previously been described. READ MORE

6. 24. The significance of low-grade inflammation in the gastrointestinal tract

   Author : David Lundgren; Pontus Karling; Mårten Werner; Klas Sjöberg; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Low-grade inflammation; gastrointestinal tract; faecal calprotectin; inflammatory bowel disease; Ulcerative colitis; irritable bowel syndrome; biomarkers; colonoscopy; proton pump inhibitors; albumin; C-reactive protein; Medicine; medicin;

   Abstract : BackgroundGastrointestinal (GI) symptoms are commonly reported in a normal population. Mostly, the symptoms are of benign cause but occasionally the symptoms can be signs of a more harmful disease. In general, it is difficult to distinguish whether the reported symptoms are caused by a benign (functional) or organic (i.e. READ MORE

7. 25. Lifestyle, biomarkers and the risk of developing inflammatory bowel disease

   Author : Lovisa Widbom; Johan Hultdin; Pontus Karling; Kim Ekblom; Kristina Stefansson; Andreas Münch; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Inflammatory bowel disease; ulcerative colitis; Crohn s disease; smoking; cotinine; iron deficiency; ferritin; pyridoxal-5-phosphate; kynurenine pathway; Clinical Chemistry; klinisk kemi; invärtesmedicin; Internal Medicine;

   Abstract : Introduction: Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn’s disease (CD), is a chronic disease causing inflammation in the gut mucosa. The pathogenesis involves alteration in gut microbiota and in the intestinal barrier due to genetic factors, environmental exposure and dysregulation of the immune response. READ MORE