Search for dissertations about: "Inflammatory joint disease"

Showing result 1 - 5 of 125 swedish dissertations containing the words Inflammatory joint disease.

  2. 1. Psoriatic arthritis: a complex disease : analyses on genetic and serological biomarkers and of comorbidity

    Author : Kristina Juneblad; Gerd-Marie Alenius; Solbritt Rantapää-Dahlqvist; Lars-Erik Kristenssen; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Psoriatic Arthritis; genetics; inflammasomes; polymorphisms; biomarkers; disease expression; disease activity; cardiovascular diseases; mortality; epidemiology;

    Abstract : Psoriatic Arthritis (PsA) is a heterogonous inflammatory arthritis associated with psoriasis. The disease leads to inflammation of peripheral joints, axial skeleton and/or enthesites, and can result in severe destruction of affected joints. READ MORE

  4. 2. Inflammatory and degenerative disease in the temporomandibular joint

    Author : Göran W Gynther; Karolinska Institutet; Karolinska Institutet; []
    Keywords : clinical findings; degenerative changes; generalized osteoarthritis; histology; immunohistochemistry; internal derangement; radiographic changes; rheumatoid arthritis; synovial inflammation; temporomandibular jointISBN 91-628-1 9;

    Abstract : Temporomandibular joint (TMJ) arthroscopy is an established technique with high diagnostic accuracy regarding synovitis and degenerative changes of the articular fibrocartilage and disk. However, so far no studies have been done to correlate the macroscopic and histologic findings with each arthroscopic criterion. READ MORE

  5. 3. Joint disease biomarkers - discovery and application

    Author : Dovilė Sinkevičiūtė; Reumatologi och molekylär skelettbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Osteoarthritis; Psoriatic arthritis; cartilage; Proteomics; Biomarkers; ELISA; Tissue culture; Extracellular matrix ECM ;

    Abstract : Dysregulated cartilage homeostasis, articular cartilage degradation and abnormal bone remodeling are common denominators in joint disease and can lead to severe disability for the patients. The molecular pathways behind the disease pathology can overlap across different joint diseases. READ MORE

  6. 4. Complement in Disease - Extracellular Proteins as Complement Regulators

    Author : Kaisa Happonen; Malmö Proteinkemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rheumatoid arthritis; joint disease; Complement; proteoglycan; cancer;

    Abstract : Complement activation occurs during inflammatory joint diseases such as rheumatoid arthritis (RA) and is thought to contribute to the chronic inflammation observed within the joints. Previous studies have shown that certain cartilage components of the small leucine-rich repeat protein (SLRP)-family regulate complement activity, thereby possibly contributing to disease progression. READ MORE

  7. 5. Genetic linkage and association studies in celiac disease: discoveries from whole genome analysis

    Author : Svetlana Adamovic; Göteborgs universitet; []
    Keywords : Celiac Disease; genome-wide scan; linkage; association; GWAS; complex disease; autoimmune; 5q31-33; HLA; IL2 IL21;

    Abstract : Celiac Disease (CD) or Gluten Sensitive Enteropathy (GSE) is a life-long disorder. It is characterized by inflammation in the small intestine of genetically predisposed individuals caused by inappropriate immune response to gluten, a protein enriched in some of our common grains (wheat, rye and barley). READ MORE