Search for dissertations about: "Influenza"

Showing result 1 - 5 of 132 swedish dissertations containing the word Influenza.

  1. 1. Influenza neuraminidase assembly Evolution of domain cooperativity

    University dissertation from Stockholm : Department of Biochemistry and Biophysics, Stockholm University

    Author : Diogo da Silveira Vieira da Silva; Robert Daniels; Ron Fouchier; [2016]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Influenza; neuraminidase; assembly; transmembrane domain; evolution; biokemi; Biochemistry;

    Abstract : Influenza A virus (IAV) is one of the most common viruses circulating in the human population and is responsible for seasonal epidemics that affect millions of individuals worldwide. The need to develop new drugs and vaccines against IAVs led scientists to study the main IAV surface antigens hemagglutinin (HA) and neuraminidase (NA). READ MORE

  2. 2. Influenza A Virus Spatial analysis of influenza genome trafficking and the evolution of the neuraminidase protein

    University dissertation from Stockholm : Department of Biochemistry and Biophysics, Stockholm University

    Author : Dan Dou; Robert Daniels; Martin Schwemmle; [2019]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Influenza A virus; IAV; neuraminidase; NA; IAV genome trafficking; viral entry; viral replication; co-infection; antigenic drift; antigenic shift; NA assembly; transmembrane domain; evolution; biokemi; Biochemistry;

    Abstract : Influenza A viruses (IAVs) are a common infectious agent that seasonally circulates within the human population that causes mild to severe acute respiratory infections. The severity of the infection is often related to how the virus has evolved with respect to the pre-existing immunity in the population. READ MORE

  3. 3. Modelling Epidemic Influenza : A Novel Approach

    University dissertation from Department of Computer and Systems Sciences, Stockholm University

    Author : Wah-Sui Almberg; Magnus Boman; Mats Danielsson; Paavo Pylkkänen; [2012]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Computer and Systems Sciences; data- och systemvetenskap;

    Abstract : Modellering av dynamiska förlopp i socio-biologiska komplexa system är långt ifrån trivialt. Behovet av fördjupad förståelse av sådana förlopp är många gånger stort. Vi har presenterat ett oortodoxt förslag på hur spridning av influensa i mänsklig population kan beskrivas och simuleras. READ MORE

  4. 4. Avian Influenza Virus Deciphering receptor interactions and their role in interspecies transmission

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Per Eriksson; Patrik Ellström; Björn Olsen; Josef D. Järhult; Åke Lundkvist; Jonas Waldenström; Hans-Dieter Klenk; [2019]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; birds; glycobiology; glycovirology; host range; mixing vessel; virus attachment; Medical Virology; Medicinsk virologi;

    Abstract : Influenza A virus (IAV) annually infects approximately 5–15 % of the human population, causing ~500,000 deaths globally. Novel IAVs have emerged and spread pandemically in the human population, but have over time established endemic circulation with reduced pathogenicity causing seasonal influenza. The natural reservoir of IAVs is wild waterfowl. READ MORE

  5. 5. Tamiflu® - Use It and Lose It?

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Josef D. Järhult; Björn Olsen; Hanna Söderström; Jonas Waldenström; Robert G. Webster; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; influenza; oseltamivir; Tamiflu; resistance development; H274Y; environment; pharmaceuticals; mallard; dabbling duck; avian influenza; influensa; resistensutveckling; miljö; läkemedel; gräsand; Infektionssjukdomar; Infectious Diseases;

    Abstract : Influenza A viruses cause seasonal and pandemic outbreaks that range from mild infections to the disastrous Spanish Flu. Resistance to neuraminidase inhibitors (NAIs) is a growing problem as these drugs constitute a vital part of treatment strategies and pandemic preparedness plans worldwide. Oseltamivir (Tamiflu®) is the mostly used NAI. READ MORE