Search for dissertations about: "Inhalable particle"

Found 4 swedish dissertations containing the words Inhalable particle.

  2. 1. Spray drying of particles intended for inhalation - Investigation of significant process variables and product characteristics, with focus on degradation and solid state properties

    Author : Kristina Mosén; Avdelningen för kemiteknik; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Läkemedelsteknik och relaterad teknik; Pharmaceutical and related technologies; carbohydrate; insulin; process conditions; crystallinity; degradation; particle size; spray drying; inhalation;

    Abstract : The interest in spray drying for production of inhalable particles has grown considerably since the late 1980s. However, which process variables that control degradation and the solid state properties have not been subject to extensive research. This thesis deals with how important characteristics of inhalation particles can be controlled, i.e. READ MORE

  4. 2. Emissions, dynamics and dispersion of particles in polluted air

    Author : Lars Gidhagen; Hans-Christen Hansson; Christer Johansson; Joakim Langner; Øystein Hov; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Meteorology; Meteorologi;

    Abstract : The main objective of this thesis is to yield information on how atmospheric fine and ultrafine particles are dispersed in populated areas. Quantitative information on emissions, transport and removal is needed to assess the health risks of inhalable particles. READ MORE

  5. 3. Cobalt in the hard metal production industry : exposure via inhalation and skin and the inflammatory response in human keratinocytes

    Author : Maria Klasson; Eva Särndahl; Håkan Westberg; Magnus Lindberg; Alexander Persson; Kristina Jakobsson; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cobalt; cobalt chloride; skin; HaCaT; in vitro; cell viability; pro-inflammatory cytokines; NLRP3 inflammasome;

    Abstract : Cobalt is a strong sensitizer and can cause contact allergy upon both direct contact or from airborne exposure on the skin. In the skin, keratinocytes are the first cells to come in contact with the metal and will react and respond to the danger by triggering an alarm system resulting in an inflammatory response in the skin. READ MORE

  6. 4. DissolvIt : development and validation of a new in vitro dissolution apparatus for dry powder aerosols

    Author : Maria Malmlöf; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Today there are no recommended dissolution methods for use in the development of new inhalable drugs. In the absence of such tailored methods, standard dissolution test methods from oral- or skin administration routes are used instead. Such methods are obviously not designed to resemble the lung environment. READ MORE