Search for dissertations about: "Institutionen för Immunteknologi"

Showing result 16 - 20 of 76 swedish dissertations containing the words Institutionen för Immunteknologi.

  2. 16. The biology of filamentous phage infection - implications for display technology

    Author : Fredrik Karlsson; Institutionen för immunteknologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biotechnology; Bioteknik; infection mechanism; selective infection; TolA; Escherichia coli; pIII; Filamentous phage; Phage display technology;

    Abstract : Phage display technology is a biotechnological tool that can be used to obtain molecules/reagents able to discriminate between target molecules. Reagents with such features can be used in diverse settings like biological chemistry, diagnostics and in therapeutic applications. READ MORE

  4. 17. A Molecular Dissection of Mantle Cell Lymphoma - From gene expression analysis to functional evaluation of selected targets

    Author : Venera Kuci; Institutionen för immunteknologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; side population; deoxycytidine kinase; resistance; SOX11; mantle cell lymphoma;

    Abstract : Mantle cell lymphoma (MCL) is an aggressive form of B-cell lymphoma (BCL) with poor clinical outcome. In this thesis, which is based upon five original papers, different approaches have been used to pinpoint and investigate molecular events that promote MCL tumor growth, progression or resistance to treatment. READ MORE

  5. 18. Molecular Recognition in Antibody Engineering. Studies on recombinant and phage displayed antibodies

    Author : Ann-Christin Malmborg Hager; Institutionen för immunteknologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; affinity; antibody; kinetic; Immunologi; serologi; serology; Immunology; Bioteknik; Biotechnology; library; selection; surface display; phage display; association rate; dissociation rate;

    Abstract : In vitro generation of antibody fragments of desired specificity and affinity plays an important role since it permits the generation of reagents which may be valuable for diagnostic and therapeutic applications. Furthermore, the kinetic parameters for an antibody-antigen interaction, rather than the affinity, has shown to correlate with biological functions like virus neutralization. READ MORE

  6. 19. Functionally-associated target antigens in cancer. Defined by human antibodies and small interfering RNAs

    Author : Johan Fransson; Institutionen för immunteknologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; phage display; Antibody; cancer; transplantation; Immunologi; serologi; serology; Immunology; onkologi; Cytologi; cancerology; oncology; Biochemistry; Metabolism; Biokemi; metabolism; Biotechnology; Bioteknik; Cytology;

    Abstract : Cancer is the collective name for diseases that have one thing in common ? uncontrolled cell growth. The increase in cancer cell proliferation eventually results in tumor formation and, in the worst case, metastatic spread to other organs. Common treatment modalities of cancer include chemotherapy and radiation therapy. READ MORE

  7. 20. Development of Computational Methods for Cancer Research: Strategies for closing the feedback loop in omics workflows

    Author : Ufuk Kirik; Institutionen för immunteknologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; cancer; proteome profiling; bioinformatics; pathway analysis; mass spectrometry; Quantitative proteomics;

    Abstract : As the ultimate workhorses of the living things, proteins undergo significant regulatory activity throughout the lifetime of a cell or an organism. Many complex diseases effect the protein composition, expression or modification in the cells or tissues they arise in. READ MORE