Search for dissertations about: "Institutionen för experimentell medicinsk vetenskap"
Showing result 21 - 25 of 100 swedish dissertations containing the words Institutionen för experimentell medicinsk vetenskap.
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21. Extracellular Matrix Remodelling-Proteoglycan and collagen turnover in arthritis
Abstract : Rheumatoid arthritis is a chronic, inflammatory and systemic disease characterised by joint destruction and pannus formation. To enlarge the understanding how pannus and granulation tissue are formed two animal models were used; one using cartilage wrapped in cotton and implanted into a rat air pouch (AP) and one where mBSA induced arthritis (AIA) was performed. READ MORE
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22. The Gastrin-ECL Cell Axis. Functional Aspects
Abstract : The ECL cells constitute a prominent endocrine cell population in the acid-producing part of the stomach. They are controlled by circulating gastrin released from G-cells in the antrum. In response to gastrin, they secrete histamine, that in turn stimulates the parietal cell to secrete acid. READ MORE
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23. PACAP in adult sensory neurons - implications in injury and pain
Abstract : The data presented in this thesis deal with the neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) in adult sensory neurons. We have used different injury and pain models to determine the involvement of PACAP during such conditions. The role of neurotrophins for PACAP expression was also investigated. READ MORE
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24. Studies of a Proteinase-activated Cell Surface Receptor
Abstract : The G protein-coupled receptors form one of the largest families of proteins involved in signalling between cells. It contains receptors for molecules as diverse as biogenic amines, glycoproteins and enzymes. The manuscripts included in this thesis together describe the initial characterisation of a previously unknown receptor of this class. READ MORE
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25. Neurogenesis in the adult brain from ballyhoo to sobriety
Abstract : New neurons are spontaneously generated in two regions of the adult brain, the hippocampus and the subventricular zone/olfactory bulb. The objective of this thesis was to study potential implications for adult neurogenesis in Alzheimer's (AD) and Parkinson's diseases (PD). READ MORE