Search for dissertations about: "Institutionen för organisk kemi."
Showing result 1 - 5 of 494 swedish dissertations containing the words Institutionen för organisk kemi..
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1. Synthesis of Biomimetic Systems for Proton and Electron Transfer Reactions in the Ground and Excited State
Abstract : A detailed understanding of natural photosynthesis provides inspiration for the development of sustainable and renewable energy sources, i.e. a technology that is capable of converting solar energy directly into chemical fuels. This concept is called artificial photosynthesis. READ MORE
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2. Investigating polymorphism in small molecules using three-dimensional electron diffraction
Abstract : For scientific, regulatory and intellectual property reasons, the discovery and characterisation of polymorphic systems is an integral aspect of the development process of any solid-formulated drug product. Yet, these studies are often hindered by crystal quality and size, poor yields and the generation of mixtures of phases. READ MORE
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3. Synthesis of Organofluorine Compounds and Allenylboronic Acids - Applications Including Fluorine-18 Labelling
Abstract : This work is focused on two areas: the chemistry of organofluorine and organoboron compounds. In the first chapter, a copper-catalysed synthesis of tri- and tetrasubstituted allenylboronic acids is presented. Extension of the same method leads to allenylboronic esters. READ MORE
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4. Design and Synthesis of Inhibitors Targeting the Aspartic Proteases HIV-1 PR and BACE-1
Abstract : This thesis describes the synthesis of molecules designed for inhibition of two aspartic proteases, viral HIV-1 PR and human BACE-1. It also reports on the structure activity relationships of the targeted enzyme inhibitors. It is estimated that currently 33 million people are infected with HIV, the causative agent of AIDS. READ MORE
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5. Asymmetric transfer hydrogenation of ketones : Catalyst development and mechanistic investigation
Abstract : The development of ligands derived from natural amino acids for asymmetric transfer hydrogenation (ATH) of prochiral ketones is described herein. In the first part, reductions performed in alcoholic media are examined, where it is found that amino acid-derived hydroxamic acids and thioamides, respectively, are simple and versatile ligands that in combination with [RhCp*Cl2]2 efficiently catalyze this particular transformation. READ MORE
