Search for dissertations about: "Insulin sensitivity"

Showing result 16 - 20 of 304 swedish dissertations containing the words Insulin sensitivity.

2. 16. Left ventricular hypertrophy and the insulin resistance syndrome

   Author : Johan Sundström; Uppsala universitet; []
   Keywords : Medical sciences; Left ventricular hypertrophy; insulin; glucose; lipids; mortality; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Geriatrics; geriatrik;

   Abstract : Left ventricular hypertrophy (LVH) and the insulin resistance syndrome are common conditions associated with a markedly increased cardiovascular risk. In a fairly large prospective longitudinal study of men from the general population, we found that an unfavorable serum fatty acid profile and components of the insulin resistance syndrome such as dyslipidemia, obesity and hypertension at age 50 predicted the prevalence of LVH at age 70. READ MORE

4. 17. Plasminogen Activator Inhibitor-1 and the Insulin Resistance Syndrome

   Author : Liisa Byberg; Anders Hamsten; Uppsala universitet; []
   Keywords : Medical sciences; PAI-1; insulin sensitivity; physical activity; birth weight; fatty acids; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Geriatrics; geriatrik;

   Abstract : In this thesis, different aspects of the insulin resistance syndrome in relation to plasminogen activator inhibitor-1 (PAI-1) activity are investigated in a longitudinal population-based study. Participants were men investigated at ages 50 and 70 with follow-up data on mortality. READ MORE

5. 18. Insulinogenic Effects of Milk- and Other Dietary Proteins, Mechanisms and metabolic implications

   Author : Mikael Nilsson; Avdelningen för livsmedel och läkemedel; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Näringslära; Nutrition; Type 2 diabetes; Isolated islets; Incretin hormones; Food proteins; Amino acids; Insulin index; Glycaemic index; Hyperinsulinaemia; Insulin; Blood glucose; Milk; Whey;

   Abstract : The metabolic syndrome (type 2 diabetes, obesity, hypertension, atherosclerotic cardiovascular disease, dyslipidaemia, and hyperinsulinaemia), is increasing in prevalence world-wide. The progression of this syndrome proceeds through a step-wise deterioration of metabolic events where deterioration of insulin sensitivity appears to have a key role in a ?vicious circle? of hyperinsulinaemia/hyperglycaemia and insulin resistance. READ MORE

6. 19. Genetic and Metabolic Markers for the Development of Diabetes after Gestational Diabetes Mellitus

   Author : Magnus Ekelund; diabetes och endokrinologi Genomik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oral glucose tolerance tests; Genetics; Autoimmunity; Insulin sensitivity; Gestational diabetes mellitus; Insulin secretion; HbA1c; Fasting glucose; FTO-gene; Postpartum diabetes;

   Abstract : The aims of this work were to determine the prevalence of postpartum diabetes among women with gestational diabetes mellitus (GDM) in a prospective study 5 years postpartum; to characterize these women according to insulin secretion, insulin sensitivity, autoimmunity and genetics; and to identify possible markers and predictors for the development of manifest diabetes. The subjects were recruited through a regional screening programme in which oral glucose tolerance tests (OGTTs) are routinely offered to all pregnant women. READ MORE

7. 20. Exploring Positional and Functional Candidate Genes for Type 2 Diabetes

   Author : Johan Holmkvist; diabetes och endokrinologi Genomik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi; MODY; type 2 diabetes; Endocrinology; calcium channel; insulin secretion; insulin; single nucleotide polymorphism SNP glucose; linkage disequilibrium; genetic association; genetics;

   Abstract : Type 2 diabetes (T2D) is a complex, metabolic disorder characterized by hyperglycaemia because of defects in insulin secretion and sensitivity. The rapid increase in T2D is likely to reflect the influence of both genetic and environmental factors in disease development. However, the genetic aetiology of T2D remains largely unknown. READ MORE