Search for dissertations about: "Insulin-producing cells"
Showing result 1 - 5 of 101 swedish dissertations containing the words Insulin-producing cells.
-
1. Protein tyrosine kinases in insulin producing cells : Expression and putative importance for beta-cell function
Abstract : Protein tyrosine kinases are of importance for cell replication and differentiation in manysystems. The mechanisms controlling the replication and differentiation of insulin producingcells are unknown. READ MORE
-
2. Glucotoxicity in Insulin-Producing β-Cells
Abstract : Background and aims: Type 2 diabetes mellitus is connected with elevated glucose levels, which cause impaired glucose-stimulated insulin secretion (GSIS) and degeneration of β-cells. Mechanisms for such glucotoxic effects were explored in the present study.Materials and methods: INS-1E cells were cultured for 5 days in 5. READ MORE
-
3. Insulin-Producing Cells, Iron, Oxidative Stress, and Lysosomal Pathology
Abstract : Accumulating evidence suggests that injnries caused by oxygen-derived radicals contribute to the destruction of pancreatic islet ß-cells in autoinnnune diabetes mellitus (diabetes type I, or IDDM). Oxidative stress may be caused by an enhanced production of oxygen-derived radicals, or by a decreased scavenging of such molecules. READ MORE
-
4. Ion dynamics in insulin-producing cells : elemental changes after momentary stimulation detected by electron and proton induced X-ray emission
Abstract : .... READ MORE
-
5. Regulation of cytokine-induced nitric oxide production in insulin-producing cells
Abstract : Cytokine-induced expression of the inducible form of nitric oxide synthase (iNOS) and production of nitric oxide (NO) may contribute to pancreatic β-cell damage during the development of type 1 diabetes. iNOS catalyses the conversion of arginine into citrulline and NO, a reaction regulated by the amount of expressed iNOS enzyme and by the cellular availability of arginine. READ MORE