Search for dissertations about: "Intact Glycoproteins"

Showing result 11 - 14 of 14 swedish dissertations containing the words Intact Glycoproteins.

  2. 11. Construction, expression and evaluation of anti-keratin 8 single-chain antibody fragments

    Author : Rozbeh Jafari; Birgitta Sundström; Jörgen Carlsson; Karlstads universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Single-chain antibody fragments; keratin 8; site-directed mutagenesis; heterologous expression; P. pastoris; design of experiments; multicellular tumor spheroids; immunotargeting; Biomedical Sciences; Biomedicinsk vetenskap;

    Abstract : Antibodies are glycoproteins specifically binding to a variety of antigens and today extensively used in prevention, diagnosis and treatment of diseases. Carcinomas originate from epithelial tissues and are the most common forms of human malignancies. In the necrotic areas of carcinomas significant amounts of keratins (K) are found extracellularly. READ MORE

  4. 12. Who is killing whom? Hantaviruses vs programmed cell death

    Author : Shawon Gupta; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Hantaviruses belong to the Bunyaviridae family of negative stranded RNA viruses. They carry a tri-segmented genome and consist of four structural proteins. The four structural proteins are two glycoproteins Gn and Gc, a nucleocapsid (N) protein and an RNA-dependent RNA-polymerase. READ MORE

  5. 13. Expression, recognition and usage of laminin-8 (a4b1g1, Lm-411) by monocytes and neutrophils

    Author : Zenebech Wondimu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Basement membrane; laminins; myeloid cells; extravasation; migration.;

    Abstract : Laminins (LNs) are a family of large alphabetagamma heterotrimeric glycoproteins found in all basement membranes (BMs). They are expressed in a tissue- and developmental stagespecific manner and implicated in vital cellular functions, including cell adhesion, migration and signaling. READ MORE

  6. 14. Biological roles of laminins 8, 9 and 10

    Author : Jill Thyboll; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : In order to form multicellular organisms, cells need attachment, either directly to each other through cell-cell interactions, or indirectly via a complex mixture of macro-molecules called the extracellular matrix. Basement membranes are specialized forms of this matrix. READ MORE