Search for dissertations about: "Intact Glycoproteins"

Showing result 6 - 10 of 14 swedish dissertations containing the words Intact Glycoproteins.

  2. 6. Laminin G Domains, their Receptors, and Activation of Intracellular Pathways

    Author : Hao Yu; Klinisk minnesforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomedicinska vetenskaper allmänt ; General biomedical sciences; cell-matrix interaction; signaling; receptor; Basement membrane; laminin;

    Abstract : Basement membranes are sheet like structures underlying epithelial, endothelial, adipocytes, muscle and peripheral nerve cells. Laminins are an important family of basement membrane proteins implicated in various biological functions through their interactions with cell surface receptors. Laminins are trimers composed of a, b and g chains. READ MORE

  4. 7. The effect of virus on the cytotoxic effector function of normal human lymphocytes

    Author : Bengt Härfast; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The cytotoxic effect of human peripheral blood lymphocytes (PBL) from healthy donors against mumps virus infected cells was studied by 5lCR-release assay. With several different cell fractionation techniques the effector cells were demonstrated to be undistinguishable from the lymphocytes responsible for antibody dependent cellular cytotoxicity (ADCC, K-cells) and from those responsible for natural cytotoxicity (NK cells). READ MORE

  5. 8. Studies of hepatitis C virus envelope proteins : interaction with host cells and as targets for the humoral response

    Author : Aster Beyene; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Hepatitis C virus; Envelope protein 1 and 2 E1 and E2 ; humoral response; VSV pseudotype.;

    Abstract : Hepatitis C virus (HCV) is a major cause of chronic hepatitis infection worldwide. It leads to chronic infection in over 80% in infected patients and may result in liver cirrhosis, hepatocellular carcinoma and autoimmune disorders. READ MORE

  6. 9. Studies of calcium binding proteins 1 and 2 and protein kinase CK2

    Author : Inger Janson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; calcium binding protein 1; calcium binding protein 2; calcium binding protein 4; erd2receptor; protein kinase CK2; endoplasmic reticulum; Golgi; microsomes; heparin; Biokemi; Biochemistry; Biokemi; Medical and Physiological Chemistry; medicinsk och fysiologisk kemi;

    Abstract : The endoplasmic reticulum (ER) is a major intracellular compartment of eukaryotic cells and is the site of the synthesis and post-translational modification of both secretory and membrane glycoproteins. Upon cell rupture vesicles of several kinds are formed from cell membranes, mainly derived from ER and are called microsomes. READ MORE

  7. 10. Effects of galectins and antibodies in HIV infection; Novel Assays

    Author : Enas Sheik-Khalil; Institutionen för laboratoriemedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1; galectin-1; galectin-8; neutralizing antibodies; cell-cell fusion; Microscale anisotropy assay; virus binding assay; glycosylation; gp120; Automated plaque reduction assay; CellProfiler; NeutNet;

    Abstract : The high variability of the HIV envelope glycoproteins (Env), and their heavy glycan coating, contributes to the limited host immune control. Still, broadly neutralizing antibodies (bnAbs) are found in some chronically infected HIV-infected individuals, which has spurred the research on antibody-based vaccines. READ MORE