Search for dissertations about: "Integrins"

Showing result 1 - 5 of 119 swedish dissertations containing the word Integrins.

  1. 1. Chemokines and Integrins in Lymphocyte Development and Localization

    University dissertation from Jan Marsal, Section fo Immunology, BMC I-13, 22184 Lund ([email protected])

    Author : Jan Marsal; Lund University.; Lunds universitet.; [2004]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunologi; serologi; transplantation; serology; Immunology; homing; development; IEL; lymphocytes; chemokines; integrins;

    Abstract : The small intestine contains a large number of T lymphocytes within the single-layered epithelium that separates the gut lumen from the lamina propria. These intraepithelial T lymphocytes have potent cytolytic and immunoregulatory capacities, thought to be important for fighting infections, neoplastic growth, and sustaining epithelial integrity. READ MORE

  2. 2. Muscle cell integrins in vitro and in vivo : Identification and characterisation of a novel integrin, α11β1

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Teet Velling; Uppsala universitet.; [2000]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; integrins; α7 integrin; α11 integrin; embryonic development; muscle; Cell- och molekylärbiologi; NATURAL SCIENCES Biology Cell and molecular biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi; molekylär cellbiologi; Molecular Cellbiology;

    Abstract : Integrins are heterodimeric receptors composed of non-covalently associated αand β subunits which have distinct functions on different cell types. α7β1integrin is an important laminin receptor in skeletal muscle. The mRNA andprotein expression patterns of α7A and α7B splice variants during mousedevelopment were studied. READ MORE

  3. 3. Functional Studies of Collagen-Binding Integrins α2β1 and α11β1 Interplay between Integrins and Platelet-Derived Growth Factor Receptors

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Gunilla Grundström; Uppsala universitet.; [2003]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; Cell- och molekylärbiologi; NATURAL SCIENCES Biology Cell and molecular biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi;

    Abstract : Integrins are heterodimeric cell surface receptors, composed of an α- and a β-subunit, which mediate cell-extracellular matrix (ECM) interactions. Integrins mediate intracellular signals in response to extracellular stimuli, and cooperate with growth factor and other cytokine receptors. READ MORE

  4. 4. Pro- and anti-inflammatory regulation of β2 integrin signalling in human neutrophils

    University dissertation from Linköping : Institutionen för biomedicin och kirurgi

    Author : Veronika Brodin Patcha; Linköpings universitet.; Linköpings universitet.; [2007]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; inflammation; neutrophils; signalling; integrins; NATURAL SCIENCES Biology Cell and molecular biology Cell biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Cellbiologi;

    Abstract : The body is under constant attack from pathogens trying to slip by our immune defence. If the barrier is breached, invading pathogens enter the tissues and cause inflammation. During this process neutrophils, constituting the first line of defence, leave the bloodstream and seek out and kill the invading pathogens. READ MORE

  5. 5. ß2 integrin-induced signal transduction events in human neutrophils

    University dissertation from Fredrik Melander Kristianstadg. 35 C 214 35 Malmö

    Author : Fredrik Melander; Lund University.; Lunds universitet.; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Inflammation; integrins; signal transduction; Rho GTPases; kinases; c-Cbl; General pathology; patologisk anatomi; pathological anatomy; Patologi allmän ; neutrophils;

    Abstract : Inflammation is a localized protective response in vascularized tissues and can be induced by microbial infection or cell and tissue injury. Polymorphonuclear neutrophils (PMN) are the most common white blood cells and are recognized as major cellular mediators of acute inflammation. READ MORE