Search for dissertations about: "Interferon-stimulated gene"
Found 5 swedish dissertations containing the words Interferon-stimulated gene.
-
1. Viperin vs. tick-borne encephalitis virus : mechanism of a potent antiviral protein
Abstract : Tick-borne encephalitis virus (TBEV) is a very important virus medically, causing mild or severe encephalitis often with long-lasting sequelae. Treatment of tick-borne encephalitis is limited to supportive care, and antiviral drugs are much needed.The type-I interferon (IFN) system is the first line of host defense against many viruses. READ MORE
-
2. On the immune response in porcine enteric diseases : with special reference to swine dysentery, proliferative enteropathy and PMWS
Abstract : Enteric infectious diseases are a common problem worldwide among pigs. It is important to gain a better knowledge about the pathogeneses of the diseases and the local immune response, in which the intestine has a very important role. READ MORE
-
3. Immunological effects of isolated regional perfusion in malignant melanoma
Abstract : Malignant melanoma patients with metastatic disease confined to the limbs or liver may be treated with hyperthermic isolated regional perfusion with a chemotherapeutic agent, most commonly melphalan. This procedure enables much higher tissue concentrations of the chemotherapeutic agent compared with systemic administration. READ MORE
-
4. Mechanisms of multicellular drug resistance and novel approaches for targeted therapy in cancer
Abstract : Dysregulated gene expression, due to genetic and epigenetic aberrations, as well as cancer cell-stroma interactions underlie both tumorigenesis and resistance to anti-cancer therapy. Although governed by common mechanisms, these features are unique to each individual tumor and therefore a personalized treatment regimen needs to be composed for each patient. READ MORE
-
5. Interfering with interferons : interplay between SARS-CoV-2 and interferon response
Abstract : Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) caused the coronavirus disease 2019 (COVID-19) pandemic, which has been an ongoing global health crisis. At the beginning of the pandemic, all the efforts were directed toward understanding the pathogenesis of the virus. READ MORE