Search for dissertations about: "Interleukin-23"

Found 3 swedish dissertations containing the word Interleukin-23.

2. 1. Interleukin-17 in models of neutrophilic lung disease

   Author : Stefan Ivanov; Göteborgs universitet; []
   Keywords : Interleukin-17; Interleukin-23; Matrix metalloproteinase-9; neutrophils; macrophages; CD4 cells; innate response; lungs;

   Abstract : Several acute or chronic lung disorders like adult respiratory distress syndrome, acute severe asthma, chronic obstructive pulmonary disease, chronic lung allograft rejection and cystic fibrosis, are associated with signs of an excess innate response in the bronchoalveolar space. Neutrophils may play a pathogenic role in these lung diseases by contributing to non-specific bronchial hyperresponsiveness and bronchial hypersecretion, as well as to epithelial damage and tissue remodelling. READ MORE

4. 2. Interleukin 15 and 17 in Staphylococcus aureus arthritis

   Author : Louise Henningsson; Göteborgs universitet; []
   Keywords : Staphylococcus aureus; Interleukin-17A; Interleukin-15; arthritis; osteoclasts; IL-23;

   Abstract : Staphylococcus aureus–induced arthritis leads to severe joint destruction and high mortality despite antibiotic treatment. Thus, there is a need to identify new treatment targets in addition to antibiotic therapy. Interleukin (IL)-15 has been implicated both in osteoclastogenesis and in bacterial clearance – two important issues in S. READ MORE

5. 3. The IL-23 axis and innate immunity in the airways

   Author : Marit Stockfelt; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IL-23; airways;

   Abstract : The Interleukin-23 (IL-23) axis is a communication system that integrates innate and adaptive immunity. When triggered by microbial stimuli, antigen presenting cells can secrete the cytokine IL-23, leading to the production of IL-17 and IL-22. READ MORE