Search for dissertations about: "Intermediate filament"

Showing result 1 - 5 of 38 swedish dissertations containing the words Intermediate filament.

  1. 1. Filament assembly and structural studies of intermediate filament like protein, FilP, in Streptomyces coelicolor

    Author : Ala Javadi; Linda Sandblad; Martin Thanbichler; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cytoskeleton; Intermediate filament-like; FilP; Streptomyces coelicolor; filament assembly; cryoelectron tomography; single particle analysis; crystallography; cellulose affinity;

    Abstract : The cytoskeleton, known as intracellular connected filaments, has a prominent role in cellular behavior, motility, and stability. The following three major types of polymers have been characterized as cytoskeleton in eukaryotes: microtubules that are 25 nm in diameter, actin filaments that are 7 nm in diameter, and intermediate filaments (IF) that are 10 nm in diameter. READ MORE

  2. 2. On the mechanics of actin and intermediate filament networks and their contribution to cellular mechanics

    Author : Björn Fallqvist; Kroon Martin; Peter McHugh; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; actin; cell; mechanical; constitutive; intermediate; continuum; constitutive; Hållfasthetslära; Solid Mechanics;

    Abstract : The mechanical behaviour of cells is essential in ensuring continued physiological function, and deficiencies therein can result in a variety of diseases. Also, altered mechanical response of cells can in certain cases be an indicator of a diseased state, and even actively promoting progression of pathology. READ MORE

  3. 3. Variability and adaptation in the contractile system of smooth muscle

    Author : Mia Löfgren; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; essential light chain; desmin; shortening velocity; integrin; intermediate filament; hypertrophy; non-muscle myosin; smooth muscle; myosin; heavy chain; Physiology; Fysiologi;

    Abstract : This thesis examines the cellular and molecular mechanisms involved in the large diversity of the contractile properties in smooth muscle. Six studies, I-VI, are included. I: a slow smooth muscle (aorta) has a different nucleotide and phosphate dependence compared to a fast type (taenia coli). READ MORE

  4. 4. Role of intermediate filament desmin in development of desmin-related myopathy

    Author : Natalia Smolina; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Desmin is a major intermediate filament of muscle cells, serving to transmit mechanical forces and propagate mechanochemical signals, to coordinate contraction and relaxation cycles, and to stabilize the positioning of cellular organelles, e.g. mitochondria. READ MORE

  5. 5. Nestin : filament formation and expression in myogenesis and muscle disorders

    Author : Gunnar Sjöberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Intermediate filament; nestin; desmin; vimentin; myogenesis neuromusculardisorders; rhabdomyosarcoma;

    Abstract : Intermediate filaments (IF), together with microfilaments and microtubules, are the major components of the cytoskeleton of eukaryotic cells. In myogenic cells three IF proteins are expressed; desmin, vimentin and nestin. READ MORE