Search for dissertations about: "Intestinal metaplasia"

Showing result 1 - 5 of 20 swedish dissertations containing the words Intestinal metaplasia.

  2. 1. The Columnar Lined Esophagus. Pathophysiological and Clinical Aspects

    Author : Stefan Öberg; Lund Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Intestinal metaplasia; Barrett s esophagus; Esophageal columnar metaplasia; Metaplasia; Pathophysiology; Gastroesophageal reflux disease; Esophagus; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi;

    Abstract : There is a persisting controversy concerning the definition, etiology and pathogenesis of Barrett's esophagus. The dramatic and parallel increase in the incidence of esophageal and junctional adenocarcinoma over the past decades justifies an evaluation of the pathophysiology of premalignant metaplastic changes of the esophagus and the gastroesophageal junction. READ MORE

  4. 2. Defence capabilities of human intestinal epithelial cells

    Author : Anna Fahlgren; Sten Hammarström; Marie-Louise Hammarström; Gudmundur Gudmundsson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; intestine; mucosa; epithelium; antimicrobial; defensins; glycocalyx; ulcerative colitis; Crohn´s disease; celiac disease; Immunologi; Immunology; Immunologi; immunologi; Immunology;

    Abstract : The epithelial cells lining the intestinal mucosa separate the underlying tissue from components of the intestinal lumen. Innate immunity mediated by intestinal epithelial cells (IECs) provides rapid protective functions against microorganisms. Innate immunity also participates in orchestrating adaptive immunity. READ MORE

  5. 3. Barrett's oesophagus and metaplasia at the oesophagogastric junction : an epidemiological approach

    Author : Johan Johansson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Barrett s oesophagus; body mass index; cardia; diagnosis; gastric mucosa; gastroscopy; gastrooesophageal reflux; Helicobacter pylori; histology; metaplasia; oesophagogastric junction. pancreatic acinar metaplasia; risk factors;

    Abstract : The aims of this thesis were to estimate the prevalence of Barrett's oesophagus (B0) and related histological aberrations, to investigate agreement between endoscopy and histology regarding the diagnosis of BO and to investigate risk factors for BO paying particular attention to epidemiological aspects of the study design. We also investigated pancreatic acinar metaplasia (PAM) with special emphasis in its relation to gastro-oesophageal reflux and BO. READ MORE

  6. 4. Ligation-mediated Molecular Analysis of Influenza Subtypes, Splicing and Protein Glycosylation

    Author : Tim Conze; Ulf Landegren; Mats Nilsson; Ola Söderberg; Jörn Glökler; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ligase; proximity ligation; gastric cancer; glycosylation; alternative splicing; avian influenza; padlock probe; Molecular medicine genetics and pathology ; Molekylär medicin genetik och patologi ; Molekylär medicin; Molecular Medicine;

    Abstract : Binder-based assays are employed throughout the life sciences. Powerful signal amplification techniques have enabled detection of very rare molecule species diluted in simple buffers. Unspecific binding of primary binders leads to increased background in more complex samples. READ MORE

  7. 5. Benign and malignant gastric mucosal changes after partial gastrectomy

    Author : Karl-Gunnar Janunger; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The development of benign and malignant mucosal changes in the gastric remnant were studied early (1-3 years) postoperatively in 55 patients and late (10-24 years) postoperatively in 336 of 676 patients subjected to partial gastrectomy for ulcer disease.Chronic gastritis with atrophy, intestinal metaplasia and cystic dilatation of the gastric glands was found early postoperatively with the same prevalence in gastric and duodenal ulcer patients. READ MORE