Search for dissertations about: "Intimal hyperplasia"

Showing result 21 - 25 of 28 swedish dissertations containing the words Intimal hyperplasia.

  2. 21. Novel markers for smooth muscle cell modulation in vascular injury and disease

    Author : Urszula Rykaczewska; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Smooth muscle cells (SMCs) are major constituents of the vascular wall, indispensable for basic physiological functions of a healthy vessel, such as regulating vascular tone and blood pressure, but also critical during disease development. With remarkable plasticity, SMCs act as early responders to vessel wall injury, where by activating molecular mechanisms, including phenotypic modulation and transdifferentiation, they counteract detrimental stimuli and aim to restore vascular homeostasis. READ MORE

  4. 22. Molecular mechanisms of cardiovascular calcification

    Author : Miguel Carracedo Ortiz; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cardiovascular calcification is a pathophysiological process characterized by the deposition of calcium-phosphate crystals in the arteries and the leaflets of the heart valves. In the arteries calcification causes arterial stiffness, which may lead to poor cardiac perfusion, systolic hypertension and heart failure. READ MORE

  5. 23. The role of FPR2/ALX in the vascular wall

    Author : Marcelo Petri; Karolinska Institutet; Karolinska Institutet; Sweden Stockholm Karolinska Institutet Dept. of Medicine; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Cardiovascular diseases caused by atherosclerosis are a leading cause of mortality worldwide. Inflammation has been described as a key component in the development of atherosclerosis. Lipoxin A4 (LXA4) is a lipid mediator derived from arachidonic acid, which has anti-inflammatory and pro-resolution properties mediated through the FPR2/ALX receptor. READ MORE

  6. 24. Vascular remodeling in pulmonary hypertension

    Author : Ya-Ting Chang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Pulmonary hypertension (PH) is a progressive obliterative vasculopathy with multifactorial etiology and high mortality rate. Endothelial dysfunction, excessive vascular remodeling, inflammation and in situ thrombosis contribute to increased vascular resistance and gradual occlusion of pulmonary vessels. READ MORE

  7. 25. On anti-diabetic agents and the vasculature

    Author : Eva Linnéa Eriksson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Diabetes is rapidly increasing worldwide, and the number of patients suffering from diabetes is projected to rise with 50 % over the next 25 years, then affecting almost 600 million adults. Type 2 diabetes comprises 90-95 % of all people with diabetes, and they constitute a patient group that carries a high burden of cardiovascular disease. READ MORE