Search for dissertations about: "Intra-Abdominal Fat"

Showing result 1 - 5 of 6 swedish dissertations containing the words Intra-Abdominal Fat.

  2. 1. Computed Tomography and Magnetic Resonance Imaging in Determination of Human Body Composition. Methodological and Applied Studies

    Author : John Brandberg; Göteborgs universitet; []
    Keywords : X-ray Computed Tomography; Magnetic Resonance Imaging; Body Composition; Obesity; Metabolic Syndrome X; Glucose Metabolism; Growth Hormone; Fatty Liver; Intra-Abdominal Fat;

    Abstract : Background: Computed tomography (CT) and magnetic resonance imaging (MRI) provide important research opportunities due to their unique capability of characterizing and quantifying tissues and organs. Ionizing radiation is a limitation using CT, and recent developments aiming to improve MRI for determination of body composition have not been validated. READ MORE

  4. 2. Transcriptional activity of PPARγ in primary human adipocytes

    Author : Lilian Sauma; Fredrik Nyström; Mats Söderström; Jan Eriksson; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : The prevalence of obesity is increasing in most parts of the world and is a strong risk factor for the development of insulin resistance, type 2 diabetes and hypertension. Adipose tissue is mainly composed of adipocytes which store energy in the form of triglycerides and release it as free fatty acids. READ MORE

  5. 3. Alterations in peripheral glucocorticoid metabolism : effects of weight changes

    Author : Kotryna Simonyté; Cecilia Mattsson; Bo Angelin; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 11ß Hydroxysteroid dehydrogenase 1; obesity; glucocorticoids; cortisol; phosphoenolpyruvate carboxykinase; adipose tissue; liver; Endocrinology; Endokrinologi; medicin; Medicine;

    Abstract : Background: An important role has been suggested for tissue-specific glucocorticoid metabolism in the development of obesity and its complications. 11ß hydroxysteroid dehydrogenase 1 (11ßHSD1) is an enzyme that catalyzes the interconversion of biologically inactive cortisone to active cortisol, thereby regulating its access to glucocorticoid receptors in target tissues. READ MORE

  6. 4. Blood Flow Regulation and Inflammatory Response in Experimental Models of Diabetes

    Author : Ulrika Pettersson; Mia Phillipson; Leif Jansson; Johanna Henriksnäs; Mikael Rydén; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Islets; beta-cells; pancreas; inflammation; obesity; adipose tissue; rats; mice; leukocytes; beta3-adrenoceptors; Medical Cell Biology; Medicinsk cellbiologi;

    Abstract : Type 2 diabetes is caused by defect pancreatic islet β-cells together with peripheral insulin resistance. The disease is often accompanied by obesity with associated low-grade visceral adipose tissue inflammation, which contributes to insulin resistance. READ MORE

  7. 5. Pathogenesis of type 2 diabetes with emphasis on the mechanism of insulin resistance

    Author : Jeanette Kuhl; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Acetyl CoA carboxylase; AMP-activated protein kinase; Glucose intolerance; Insulin secretion; Insulin sensitivity; Malonyl CoA; Malonyl CoA decarboxylase; Peroxisomal proliferator activated receptor ã co-activator 1 á; Type 2 diabetes heredity;

    Abstract : Type 2 diabetes is characterized by chronic hyperglycemia and develops slowly through stages of early impairments of glucose metabolism. The disease is often associated with obesity, physical inactivity, decreased insulin sensitivity and impaired insulin responsiveness. READ MORE