Search for dissertations about: "Intracellular Membranes chemistry"

Showing result 1 - 5 of 6 swedish dissertations containing the words Intracellular Membranes chemistry.

  2. 1. α-Synuclein Fibril Formation and the Effects of Lipid Membranes

    Author : Ricardo Gaspar; Fysikalisk kemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Protein misfolding; alpha-synuclein; Parkinson s disease; microscopic rate constants; Thioflavin T; ganglioside lipids; Exosomes; protein-lipid co-aggregation; model membranes; monomer-dependent secondary nucleation;

    Abstract : Amyloid protein aggregation results in major disturbances of cellular processes in humans. The most common amyloid-related disorders are Alzheimer´s disease and Parkinson´s disease. Parkinson´s disease is charaterized by the formation of protein-rich aggregates that are deposited in neurons, termed Lewy bodies and Lewy neurites. READ MORE

  4. 2. Interaction of Calcium Ions with Lipid Membranes

    Author : Baharan Ali Doosti; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; phospholipid bilayer membrane; membrane dynamics; micromanipulation; calcium ions; cell migration.; membrane nanotube; membrane tubular protrusions; calcium ion concentration gradient; membrane bending; giant unilamellar vesicle;

    Abstract : Bilayer membranes enclose and shield the biological cell and its inner compartments, as well as the tubular networks that exist within and between the cells. Due to their fluidic nature, the membranes are incredibly dynamic and flexible, which allows them to bend, reshape and fuse in response to mechanical and chemical stimuli within their natural microenvironments. READ MORE

  5. 3. Rational design of nanoparticles for biomedical imaging and photovoltaic applications

    Author : Haiyan Qin; Hans Ågren; Alexander Dmitriev; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Theoretical chemistry; Teoretisk kemi;

    Abstract : This thesis aims to rationally design nanoparticles and promote their applications in biomedical imaging and photovoltaic cells. Quantum dots (QDs) are promising fluorescent probes for biomedical imaging. READ MORE

  6. 4. Intracellular Uptake and Membrane Binding of Cell-penetrating Peptides: The Influence of Arginines, Tryptophans and Proteoglycans

    Author : Hanna Rydberg; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell-penetrating peptides; membrane-binding; cellular uptake; proteoglycans; tryptophan; arginine-rich peptide;

    Abstract : One of the major limitations in the realization of functional gene therapy is efficient intracellular transport of the therapeutic macromolecules. Amongst several different techniques, cell-penetrating peptides (CPPs) have emerged as promising candidates for this purpose. READ MORE

  7. 5. Methods for elucidating membrane protein structure and function

    Author : Carolina Trkulja; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; patch clamp; antibodies; mass spectrometry; ion channels; proteomics; fluorescence; TRPV1; cholesterol.; limited proteolysis; Membrane proteins;

    Abstract : Elucidation of the structure-function relationship of membrane proteins increases our understanding of many biological processes, both physiological and pathological. However, membrane proteins have been notoriously difficult to study, having part of their structure embedded into the lipid cell membrane. READ MORE