Search for dissertations about: "Intraepithelial lymphocytes IELs"

Found 4 swedish dissertations containing the words Intraepithelial lymphocytes IELs.

  2. 1. Butyrophilin- and Butyrophilin-like genes and their role in epithelial cell-intraepithelial T lymphocyte cross-talk

    Author : Cristina Lebrero-Fernandez; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Butyrophilin-like Btnl ; Butyrophilin Btn ; Intraepithelial lymphocytes IELs ; Mucosal immunity; Intestinal epithelial cells; γδ T cells; Intestinal inflammation; Colon cancer; Ulcerative colitis;

    Abstract : More than 50% of our immune system is located in the gut. The intestinal epithelium, which forms an interface between the organism and the environment, harbors intraepithelial lymphocytes (IELs) that comprise a mixture of conventional αβ T cells and unconventional αβ- and γδ T cells. READ MORE

  4. 2. Innate and adaptive immunity in childhood celiac disease

    Author : Göte Forsberg; Marie-Louise Hammarström; Riccardo Troncone; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immunologi; Immunology;

    Abstract : Celiac disease (CD) is an inflammatory small-bowel enteropathy caused by a permanent intolerance to wheat gluten and related proteins in rye and barley. Even though the disease originate from the small intestine the clinical symptoms varies in affected individuals and are often different in small children compared to adolescents and adults. READ MORE

  5. 3. Dynamic changes in T cell compartments and new approaches in evaluating DSS induced and Gai2 deficient colitis

    Author : Maria Fritsch Fredin; Göteborgs universitet; []
    Keywords : colitis; Gai2- - mice; dextran sodium sulfate; ex vivo cultures; micro-Computed Tomography; IEL; thymus; Inflammatory Bowel Disease;

    Abstract : The overall aim of this thesis was to increase the understanding of the immunopathology of Inflammatory Bowel Disease (IBD). The first aim was to elucidate how the thymus and the gut epithelium were affected by colitis. The second aim was to investigate new ways of assessing and monitoring colitis. READ MORE

  6. 4. Innate immunity of human intestinal epithelium in childhood celiac disease : influences from celiac disease associated bacteria and dietary oats

    Author : Grzegorz Pietz; Marie-Louise Hammarström; Thomas T MacDonald; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Celiac disease; dietary oats; gut microbiota; intestinal epithelium; IEL; IFN-γ; IRF1; IL-18; CXC3L1; inflammasome; permeability; Prevotella jejuni; Lachnoanaerobaculum umeaense; immunologi; Immunology;

    Abstract : Background & Aims: Celiac disease (CD) is a chronic inflammatory small-bowel enteropathy caused by permanent intolerance to gliadin in wheat gluten, and related proteins in ray and barley. It is disputed whether CD patients tolerate oats. The only treatment of CD is lifelong gluten-free diet (GFD). READ MORE