Search for dissertations about: "Introns"

Showing result 6 - 10 of 61 swedish dissertations containing the word Introns.

  2. 6. Biochemical and structural studies of pre-mRNA splicing

    Author : Ingela Wetterberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Gene expression; pre-mRNA processing; transcription; in situ; electron tomography;

    Abstract : When eucaryotic genes are expressed, they are transcribed into pre-mRNAs (precursor mRNAs) that need extensive processing before they can be exported from the nucleus as mRNAs and translated into proteins in the cytoplasm. One central processing event is splicing, which means removal of intervening, non-coding sequences, introns and joining of functional sequences, exons. READ MORE

  4. 7. Regulation of adenovirus alternative pre-mRNA splicing : Functional characterization of exonic and intronic splicing enhancer elements

    Author : Bai-Gong Yue; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; adenovirus; pre-mRNA splicing; splicing enhancer; MLTU; L1; SR protein; ASF SF2; E. coli; phosphorylation; dephosphorylation; Biokemi; Biochemistry; Biokemi; mikrobiologi; Microbiology;

    Abstract : Pre-mRNA splicing and alternative pre-mRNA splicing are key regulatory steps controlling geneexpression in higher eukaryotes. The work in this thesis was focused on a characterization of thesignificance of exonic and intronic splicing enhancer elements for pre-mRNA splicing. READ MORE

  5. 8. Mutation and Diversity in Avian Sex Chromosomes

    Author : Hannah Sundström; Hans Ellegren; David W. Burt; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; mutation rate; diversity; sex chromosomes; indels; male bias; selective sweep; effective population size; birds; Genetik; Clinical genetics; Klinisk genetik;

    Abstract : Sex chromosomes are useful for the study of how factors such as mutation, selection, recombination and effective population size affect diversity and divergence.A comparison of gametologous introns in seven different bird species revealed a complete lack of diversity on the female-specific W chromosome. READ MORE

  6. 9. Phylogenetic Support and Chloroplast Genome Evolution in Sileneae (Caryophyllaceae)

    Author : Per Erixon; Bengt Oxelman; Sean Graham; Uppsala universitet; []
    Keywords : Biology; Phylogenetics; Bayesian inference; Bootstrapping; cpDNA; Sileneae; Interspecific chloroplast recombination; Hybridization; clpP; Positive selection; Extreme substitution rates; Biologi;

    Abstract : Evolutionary biology is dependent on accurate phylogenies. In this thesis two branch support methods, Bayesian posterior probablities and bootstrap frequencies, were evaluated with simulated data and empirical data from the chloroplast genome. READ MORE

  7. 10. Pre-mRNA processing in the polytene nuclei of chironomus tentans

    Author : Göran Baurén; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Pre-mRNA processing; Organization of splicing factors; Cotranscriptionalsplicing; Transcription termination; Chironomus tentans; Polytene nuclei.;

    Abstract : Gene expression of protein encoding genes in eukaryotic cells requires extensive intranuclear maturation processing of the transcribed pre-mRNA. Three such processes are known to occur. The 5' end is capped and the 3' end is determined by cleavage and polyadenylation. READ MORE