Search for dissertations about: "Invasion and Proliferation in Malignant Cells"

Showing result 1 - 5 of 24 swedish dissertations containing the words Invasion and Proliferation in Malignant Cells.

  2. 1. Invasion and Proliferation in Malignant Cells

    Author : Sofie Svensson Månsson; Malmö Patologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancerology; oncology; Cytology; breast cancer; squamous cell carcinoma; basal cell carcinoma; p16; proliferation; invasion; Cytologi; onkologi; cancer;

    Abstract : Two key events in the oncogenic process of tumor cells are to acquire uncontrolled proliferation and invasive properties. This allows the tumor to grow and invade beyond the tissue from which the tumor cells originate. READ MORE

  4. 2. Proliferation, Invasion and p16 Localisation in Malignancies

    Author : Kristina Nilsson; Malmö Patologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; onkologi; Cytologi; cancerology; Cytology; oncology; skin tumours; invasion; p16; cancer; patologisk anatomi; Patologi allmän ; pathological anatomy; proliferation; General pathology;

    Abstract : Uncontrolled proliferation and invasion are two characteristics in tumour development and progression. Previous studies have shown that invading tumour cells in colorectal cancer have low proliferation in parallel to upregulation of the tumour suppressor p16. READ MORE

  5. 3. Expression and function of the protein tyrosine phosphatases SHP-1 and SHP-2 in prostate cancer

    Author : Helena Tassidis; Institutionen för translationell medicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer SHP-1SHP-2 IL-6phosphorylationsignalling pathways;

    Abstract : Prostate cancer is one of the most frequent cancers in males in Western countries. Radical prostatectomy serves as the first line of treatment for patients with localised prostate cancer. However, in many cases the cancer will recur. It is currently difficult to identify those patients at a high risk of tumour recurrence. READ MORE

  6. 4. Reversal of thyroid dedifferentiation and an invasive phenotype by small molecule kinase inhibitors: an experimental study on normal and malignant cells

    Author : Camilla Ingeson-Carlsson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; thyroid; cancer; NIS; MAPK; PI3K; BRAFV600E; migration; 3D culture;

    Abstract : Refractoriness to I-131 in dedifferentiated thyroid cancer is a great concern that restricts radioiodine therapy. There is also a lack of knowledge in understanding the mechanisms leading to repressed sodium iodide symporter (NIS) expression and impaired iodide uptake in tumor cells. READ MORE

  7. 5. Alpha 1-antitrypsin: A Role in Cancer Progression

    Author : Inga Zelvyté; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer; onkologi; Cytologi; cancerology; oncology; Cytology; invasion; neutrophils; cancer cell; Alpha1- antitrypsin; proteinase inhibitors;

    Abstract : Alpha1-antitrypsin (AAT), a circulating single-chain glycoprotein is the most abundant serine proteinase inhibitor in human plasma. AAT is an acute phase protein, its levels increase rapidly to concentrations exceeding 50mM in response to inflammation, infection and malignant diseases. READ MORE