Search for dissertations about: "Iontophoresis"
Showing result 1 - 5 of 16 swedish dissertations containing the word Iontophoresis.
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1. Electrochemical Methods for Drug Characterisation and Transdermal Delivery : Capillary Zone Electrophoresis, Conductometry, and Iontophoresis
Abstract : This thesis concerns the development and utilisation of techniques for characterisation and transdermal delivery of various systems for pharmaceutical applications.The degree of dissociation of drug molecules and the mobilities of the different species formed are essential factors affecting the rate of drug delivery by iontophoresis. READ MORE
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2. Assessment of microvascular function by use of transdermal iontophoresis : methodological aspects
Abstract : Assessment of the microcirculation is of major importance in understanding the physiology of the vasculature and in assessing te vascular effects of pathological conditions such as diabetes, hypertension and sepsis. Transdermal iontophoresis can be used to non‐invasively introduce vasoactive drugs into the skin. READ MORE
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3. ALA and m-ALA in bicontinuous lipid formulations: -Characterization and Transdermal Delivery
Abstract : δ-Aminolevulinic acid (ALA) and its methyl ester (m-ALA) are both used in photodynamic therapy (PDT) of certain non melanoma skin cancers as the basal cell carcinoma (BCC). In PDT the cancer cells are destroyed by a photochemical reaction that occurs when a photosensitive molecule is irradiated with light of a certain wavelength. READ MORE
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4. Assessment of microvascular effects of vasoactive drugs : Methodological in vivo studies in humansbased on iontophoresis
Abstract : Cardiovascular disease is the leading cause of death in western societies and endothelial dysfunction is one of the earliest signs seen in the development of such conditions. Thedevelopment of prognostic tools to aid in the prediction of micro- and macrovascular diseasebased on assessment of vascular reactivity is therefore of paramount importance. READ MORE
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5. Assessment of microvascular and metabolic responses in the skin
Abstract : The general aim of this project was to develop experimental in vivo models that allow for minimally invasive investigations of responses in the skin to microvascular and metabolic provocations. The cutaneous microvasculature has emerged as a valuable model and been proposed to mirror the microcirculation in other organs. READ MORE