Search for dissertations about: "Iressa"

Found 3 swedish dissertations containing the word Iressa.

  2. 1. Tumour Targeting Using Radiolabelled EGF Conjugates : Preclinical Studies

    Author : Åsa Liljegren Sundberg; Jörgen Carlsson; Lars Gedda; Vladimir Tolmachev; Erik Blomquist; Gregory P. Adams; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Radiation sciences; targeting; tumour; EGF; radionuclide; gefitinib; Iressa; ZD1839; glioma; therapy; diagnostics; Strålningsvetenskap; Radiation biology; Strålningsbiologi;

    Abstract : Tumour targeted radiotherapy is an appealing approach for treatment of disseminated tumour cells. A targeting agent that specifically binds to a structure on tumour cells is then used to transport therapeutically relevant radionuclides. The epidermal growth factor receptor, EGFR, is overexpressed on tumour cells in several malignancies, e.g. READ MORE

  4. 2. The uPA receptor in ovarian cancer. Regulation by EGF and the estrogen responsive membrane receptor GPR30. Soluble uPAR in diagnosis and prognosis

    Author : Emir Henic; Lund Obstetrik och gynekologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; G-1.; GPR30; suPAR; prognosis; estradiol; ovarian cancer; EGFR; ER; diagnosis;

    Abstract : Cell migration is the first step of the invasive process, which is part of the malignant phenotype, and the uPA receptor (uPAR) plays a central role in cell migration. We studied the role of EGF and estrogen on cell migration and uPAR expression in ovarian cancer cell lines. READ MORE

  5. 3. Post-translational modifications of proteins in human breast cancer : proteomics studies of phosphorylation and nitration and implication of these PTMs in tumorigenesis

    Author : Min Jia; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Breast cancer is the most common cancer in women. Even though improvements in diagnosis and treatment of breast cancer have been made, it is still the most common cause of cancer death in women. There is a great need to find biomarkers for early detection of the disease and novel drug targets to fight the cancer. READ MORE